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AstraZeneca Shows the Risk of Investing in Coronavirus Vaccine Stocks – Motley Fool

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AstraZeneca (NYSE:AZN) has long been considered a leader in the COVID-19 vaccine race. The company is developing its candidate, AZD1222, in collaboration with the University of Oxford. The drugmaker was fast out of the gate, and was one of the first to start a phase 2/3 clinical trial for its experimental vaccine back in May. AstraZeneca has also penned deals with the U.S. government and the European Union (EU) to supply millions of doses of its vaccine, pending regulatory approval.

Few companies in this race have landed such agreements, which shows that these governments also view AZD1222 as one of the most promising candidates. However, AstraZeneca just hit a bit a roadblock in its quest to bring its COVID-19 program to completion. Its paused research serves as a warning sign and important reminder to investors looking to profit from coronavirus vaccine development efforts.

Image source: Getty Images.

Word travels fast 

On Sept. 8, news broke via online trade publication, STAT, that AstraZeneca’s phase 3 study in the U.K. for AZD1222 had to be put on hold. The reason? One of the participants in the study suffered from a severe adverse reaction. “Standard review process triggered a pause to vaccination to allow review of safety data,” according to a spokesperson for the company. 

Investors do not have a totally complete picture of the participant’s medical status, but the person did display “serious neurological symptoms” following inoculation, according to STAT. Based on publicly available information, it is unknown whether AZD1222 directly caused the adverse reaction. But what little information we do have was enough to stir up a market reaction. AstraZeneca’s stock dropped by about 8% in after-hours trading on Sept. 8. 

An important risk reminder

AstraZeneca’s stock rebounded relatively swiftly on Sept. 9, as it became clear that the initial news of a pause wasn’t as damaging to the entire program as it seemed. Matt Hancock, Health Minister of the U.K., said that the decision to halt the trial momentarily was not necessarily a setback. Given that the study features about 30,000 participants, it isn’t too surprising that one of them suffered from a serious illness during the investigation. Hitting the pause button to delve into the matter further is the standard course of action during clinical trials like this one, and it is not a certain signal that there is anything wrong with the vaccine.

But this is a reminder that clinical trials are rife with potential pitfalls, and running into one of these obstacles can sink a company’s stock. Note that AstraZeneca’s shares are up 7.7% year to date, which isn’t that much better than the 3.3% gains of the S&P 500 since the beginning of the year. Has the company’s stock been boosted purely by its COVID-19 program? 

AZN Chart

AZN data by YCharts

AstraZeneca’s stock has most definitely benefitted from its vaccine development, but before the pandemic, it was already a well-established pharma company with multiple products in its lineup that generated strong sales. Over the trailing-12-month period, the company racked up $25.7 billion in revenue and $2.15 billion in net income. The healthcare giant also has well over 100 programs in its pipeline. In other words, even if it fails to launch a safe and effective coronavirus vaccine, AstraZeneca will survive. By contrast, companies such as Inovio Pharmaceuticals (NASDAQ:INO) and Moderna (NASDAQ:MRNA) currently have no products on the market, and the success of their COVID-19 programs is, to a large extent, well-baked into their stock prices. 

Inovio’s stock is up by 202.4% year to date, and the company boasts a market cap of $1.67 billion — up from a measly $325.37 million on Jan. 2. These gains have been almost entirely driven by its efforts to develop a vaccine for COVID-19. Any roadblock, be it real or perceived, could send its stock crashing down. Moderna is in the same boat; the company’s shares are up by 199.1% and its market cap is $23.11 billion, up from $6.47 billion on Jan. 2. Moderna’s market cap seems too high for a clinical-stage biotech company, which indicates that investors are betting big that the company will benefit from its COVID-19 program. If Moderna runs into a roadblock along the way, its stock could also fall off a cliff. 

The key takeaway for coronavirus company investors

Inovio and Moderna could go on to successfully launch their respective vaccines on the market. But because of the uncertainties that plague clinical trials, and considering that neither has an approved and marketed product, both are high-risk, high-reward plays. For aggressive investors interested in either stock, it’d be best to initiate a small position and continuously monitor the progress of their coronavirus-related clinical trials. Risk-averse investors, on the other hand, will probably want to steer clear of both of these companies, and may feel that buying a few shares of a stalwart like AstraZeneca affords enough exposure to the coronavirus vaccine market without the serious possibility of the pharma stock‘s plummet. 

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Canada Goose to get into eyewear through deal with Marchon

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TORONTO – Canada Goose Holdings Inc. says it has signed a deal that will result in the creation of its first eyewear collection.

The deal announced on Thursday by the Toronto-based luxury apparel company comes in the form of an exclusive, long-term global licensing agreement with Marchon Eyewear Inc.

The terms and value of the agreement were not disclosed, but Marchon produces eyewear for brands including Lacoste, Nike, Calvin Klein, Ferragamo, Longchamp and Zeiss.

Marchon plans to roll out both sunglasses and optical wear under the Canada Goose name next spring, starting in North America.

Canada Goose says the eyewear will be sold through optical retailers, department stores, Canada Goose shops and its website.

Canada Goose CEO Dani Reiss told The Canadian Press in August that he envisioned his company eventually expanding into eyewear and luggage.

This report by The Canadian Press was first published Sept. 19, 2024.

Companies in this story: (TSX:GOOS)

The Canadian Press. All rights reserved.

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A timeline of events in the bread price-fixing scandal

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Almost seven years since news broke of an alleged conspiracy to fix the price of packaged bread across Canada, the saga isn’t over: the Competition Bureau continues to investigate the companies that may have been involved, and two class-action lawsuits continue to work their way through the courts.

Here’s a timeline of key events in the bread price-fixing case.

Oct. 31, 2017: The Competition Bureau says it’s investigating allegations of bread price-fixing and that it was granted search warrants in the case. Several grocers confirm they are co-operating in the probe.

Dec. 19, 2017: Loblaw and George Weston say they participated in an “industry-wide price-fixing arrangement” to raise the price of packaged bread. The companies say they have been co-operating in the Competition Bureau’s investigation since March 2015, when they self-reported to the bureau upon discovering anti-competitive behaviour, and are receiving immunity from prosecution. They announce they are offering $25 gift cards to customers amid the ongoing investigation into alleged bread price-fixing.

Jan. 31, 2018: In court documents, the Competition Bureau says at least $1.50 was added to the price of a loaf of bread between about 2001 and 2016.

Dec. 20, 2019: A class-action lawsuit in a Quebec court against multiple grocers and food companies is certified against a number of companies allegedly involved in bread price-fixing, including Loblaw, George Weston, Metro, Sobeys, Walmart Canada, Canada Bread and Giant Tiger (which have all denied involvement, except for Loblaw and George Weston, which later settled with the plaintiffs).

Dec. 31, 2021: A class-action lawsuit in an Ontario court covering all Canadian residents except those in Quebec who bought packaged bread from a company named in the suit is certified against roughly the same group of companies.

June 21, 2023: Bakery giant Canada Bread Co. is fined $50 million after pleading guilty to four counts of price-fixing under the Competition Act as part of the Competition Bureau’s ongoing investigation.

Oct. 25 2023: Canada Bread files a statement of defence in the Ontario class action denying participating in the alleged conspiracy and saying any anti-competitive behaviour it participated in was at the direction and to the benefit of its then-majority owner Maple Leaf Foods, which is not a defendant in the case (neither is its current owner Grupo Bimbo). Maple Leaf calls Canada Bread’s accusations “baseless.”

Dec. 20, 2023: Metro files new documents in the Ontario class action accusing Loblaw and its parent company George Weston of conspiring to implicate it in the alleged scheme, denying involvement. Sobeys has made a similar claim. The two companies deny the allegations.

July 25, 2024: Loblaw and George Weston say they agreed to pay a combined $500 million to settle both the Ontario and Quebec class-action lawsuits. Loblaw’s share of the settlement includes a $96-million credit for the gift cards it gave out years earlier.

Sept. 12, 2024: Canada Bread files new documents in Ontario court as part of the class action, claiming Maple Leaf used it as a “shield” to avoid liability in the alleged scheme. Maple Leaf was a majority shareholder of Canada Bread until 2014, and the company claims it’s liable for any price-fixing activity. Maple Leaf refutes the claims.

This report by The Canadian Press was first published Sept. 19, 2024.

Companies in this story: (TSX:L, TSX:MFI, TSX:MRU, TSX:EMP.A, TSX:WN)

The Canadian Press. All rights reserved.

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TD CEO to retire next year, takes responsibility for money laundering failures

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TORONTO – TD Bank Group, which is mired in a money laundering scandal in the U.S., says chief executive Bharat Masrani will retire next year.

Masrani, who will retire officially on April 10, 2025, says the bank’s, “anti-money laundering challenges,” took place on his watch and he takes full responsibility.

The bank named Raymond Chun, TD’s group head, Canadian personal banking, as his successor.

As part of a transition plan, Chun will become chief operating officer on Nov. 1 before taking over the top job when Masrani steps down at the bank’s annual meeting next year.

TD also announced that Riaz Ahmed, group head, wholesale banking and president and CEO of TD Securities, will retire at the end of January 2025.

TD has taken billions in charges related to ongoing U.S. investigations into the failure of its anti-money laundering program.

This report by The Canadian Press was first published Sept. 19, 2024.

Companies in this story: (TSX:TD)

The Canadian Press. All rights reserved.

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