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AI shows major promise in breast cancer detection, new studies suggest

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Despite promising findings, researchers say technology still has limitations

Researchers experimenting with artificial intelligence have found that these tools seem to reliably detect breast cancer, while also reducing a demanding workload for radiologists.

Breast cancer is the most common cancer among adults, with more than 2.3 million cases diagnosed each year, according to the World Health Organization. In most countries, the illness is one of the top two leading causes of cancer deaths in women.

But research shows (new window) that early detection and treatment can save lives.

To increase screening capacity and better identify high and low risk breast cancer, two recent studies show that specific applications of artificial intelligence (AI) performed similarly to highly trained radiologists.

I think that breast imaging, especially mammography, [is] one of the front runners when it comes to the maturity of these AI tools, said Kristina Lång, lead author on one of the studies.

Lång’s research, which was published in the Lancet Oncology journal (new window) last month, is the first of its kind to use AI to detect breast cancer from mammograms in a randomized control trial.

Preliminary results of the Swedish trial show that AI detected more cancer, while keeping false positives to a minimum.

The results were actually [above] our expectations, said Lång, a breast radiologist and associate professor at Lund University in Sweden.

Another smaller study, published earlier this week (new window) in the journal Radiology, found that radiologists and AI came to similar conclusions after reviewing the same mammograms.

These recent studies are practical examples of the way AI could be used in healthcare to relieve a strained workforce, while ensuring more accurate diagnoses, say experts like Lång.

But other experts warn that the technology is still being refined to ensure it doesn’t over diagnose or miss the cancer.

AI reduced radiologist workload

Radiologists are placing extra significance on Lång’s research as it randomly assigned mammograms from more than 80,000 women to two groups.

One group involved AI-supported screening and the other followed double reading — a standard practice in Europe where two radiologists independently review each mammogram.

In the AI-supported group, the software triaged the scans by determining which ones were of low risk and needed only one radiologist to look at them, or high risk, requiring two radiologists.

Results found that the AI-supported screening group detected about 20 per cent more cancers. It also had a similar number of false positives and women recalled for further analysis as the standard group.

Due to the triaging, the radiologists in the AI-supported screening group read about 44 per cent fewer mammograms than those in the standard group.

It’s a difficult task to read large volumes of screening examinations in order to detect these small subtle cancers, said Lång. You have to be alert.

Additionally, she said radiology is experiencing a significant worker shortage (new window), so these results show the value of AI in areas with limited staff.

AI can over diagnose, have trouble with dense breasts

We should be embracing this technology as a really helpful tool to do better and try and diagnose more cancers at an early stage, said Jean Seely, who heads the breast imaging section at the Ottawa Hospital.

But she said there are still some issues that need to be refined.

In particular, Lång’s study found that AI can over diagnose cancers that might not end up being harmful to the patient.

We want to call only those patients that really have cancer, but there’s a fine line that we have to balance, said Seely, who is also a radiology professor at the University of Ottawa.

She also said that, at this point, AI doesn’t compare the current mammogram it’s reading to past ones, nor does it know that the patient might have already had a biopsy for a certain abnormality.

So to rely on the AI only is really impossible, said Seely, adding that radiologists are also legally responsible for the mammogram interpretation.

You have to have a trained person, radiologist, to be able to read those cases and say, ‘yeah this is an appropriate recall, but this is not.’

Dr. Mojola Omole, a breast oncologist and surgeon in Ontario’s Scarborough Health Network, also thinks AI shows promise for the future, but she’s concerned with the technology’s ability to detect breast cancer in women with more dense tissue (new window).

Typically, she said, Black and Asian women can have more dense breast tissue, which hides the cancer.

What I worry about sometimes, when we talk about AI medicine, is that populations such as racialized people, when it comes to breast cancer, are not necessarily going to be represented in that sample, she said.

Omole noted that in the Swedish trial, the race and ethnicity of the women wasn’t recorded.

If women of all backgrounds aren’t included in research like this, said Omole, then it might mean that AI could misdiagnose them or miss the cancer completely.

Dr. Martin Yaffe, a professor and senior scientist at Sunnybrook Research Institute in Toronto, said his team is working on AI that can detect breast density and calculate the chances of a hidden cancer.

We’re stepping carefully to try and avoid doing anything foolish to get this new technology so that it’s ready for prime time and that involves a lot of testing, and testing under a wide variety of circumstances, he said.

More research needed to determine tool’s success

Unlike in Europe, mammograms aren’t screened by two radiologists in Canada.

As a result, Ottawa-based radiologist Seely said more research is needed to know how AI would work in the Canadian context.

She notes that it shouldn’t replace a human, but that it adds more value.

And that’s what breast cancer survivor Marilyn Jordan also thinks about it.

I feel positive about AI facilitating quicker diagnosis and catching more cancers than at the current time, said the 68-year-old Vancouver resident.

Jordan completed her breast cancer treatment last September after she pushed to get a mammogram a year before her regularly scheduled screening appointment.

Even though AI can over diagnose, Jordan said she’d rather the tool be extra cautious and catch everything.

Maybe it’ll find a cyst that needs to be monitored annually, she said.

The Swedish trial is still ongoing and looks to better evaluate AI-supported screening by finding out whether it reduces the rate of interval cancer.

Interval cancer is when a person is diagnosed with cancer after a normal result and before their next screening appointment.

The interval cancer rate will be determined after the participants have a follow-up two years from their screening in December 2024.

Lång said they’re also interested to know whether the use of AI is cost effective.

I think the synergistic effect, when humans work together with this AI tool, to use them in a safe and smart way, we can really … improve both the efficiency and the quality of healthcare.

 

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What’s the greatest holiday gift: lips, hair, skin? Give the gift of great skin this holiday season

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Give the gift of great skin this holiday season

Skinstitut Holiday Gift Kits take the stress out of gifting

Toronto, October 31, 2024 – Beauty gifts are at the top of holiday wish lists this year, and Laser Clinics Canada, a leader in advanced beauty treatments and skincare, is taking the pressure out of seasonal shopping. Today, Laser Clincs Canada announces the arrival of its 2024 Holiday Gift Kits, courtesy of Skinstitut, the exclusive skincare line of Laser Clinics Group.

In time for the busy shopping season, the limited-edition Holiday Gifts Kits are available in Laser Clinics locations in the GTA and Ottawa. Clinics are conveniently located in popular shopping centers, including Hillcrest Mall, Square One, CF Sherway Gardens, Scarborough Town Centre, Rideau Centre, Union Station and CF Markville. These limited-edition Kits are available on a first come, first served basis.

“These kits combine our best-selling products, bundled to address the most relevant skin concerns we’re seeing among our clients,” says Christina Ho, Senior Brand & LAM Manager at Laser Clinics Canada. “With several price points available, the kits offer excellent value and suit a variety of gift-giving needs, from those new to cosmeceuticals to those looking to level up their skincare routine. What’s more, these kits are priced with a savings of up to 33 per cent so gift givers can save during the holiday season.

There are two kits to select from, each designed to address key skin concerns and each with a unique theme — Brightening Basics and Hydration Heroes.

Brightening Basics is a mix of everyday essentials for glowing skin for all skin types. The bundle comes in a sleek pink, reusable case and includes three full-sized products: 200ml gentle cleanser, 50ml Moisture Defence (normal skin) and 30ml1% Hyaluronic Complex Serum. The Brightening Basics kit is available at $129, a saving of 33 per cent.

Hydration Heroes is a mix of hydration essentials and active heroes that cater to a wide variety of clients. A perfect stocking stuffer, this bundle includes four deluxe products: Moisture 15 15 ml Defence for normal skin, 10 ml 1% Hyaluronic Complex Serum, 10 ml Retinol Serum and 50 ml Expert Squalane Cleansing Oil. The kit retails at $59.

In addition to the 2024 Holiday Gifts Kits, gift givers can easily add a Laser Clinic Canada gift card to the mix. Offering flexibility, recipients can choose from a wide range of treatments offered by Laser Clinics Canada, or they can expand their collection of exclusive Skinstitut products.

 

Brightening Basics 2024 Holiday Gift Kit by Skinstitut, available exclusively at Laser Clincs Canada clinics and online at skinstitut.ca.

Hydration Heroes 2024 Holiday Gift Kit by Skinstitut – available exclusively at Laser Clincs Canada clinics and online at skinstitut.ca.

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Here is how to prepare your online accounts for when you die

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LONDON (AP) — Most people have accumulated a pile of data — selfies, emails, videos and more — on their social media and digital accounts over their lifetimes. What happens to it when we die?

It’s wise to draft a will spelling out who inherits your physical assets after you’re gone, but don’t forget to take care of your digital estate too. Friends and family might treasure files and posts you’ve left behind, but they could get lost in digital purgatory after you pass away unless you take some simple steps.

Here’s how you can prepare your digital life for your survivors:

Apple

The iPhone maker lets you nominate a “ legacy contact ” who can access your Apple account’s data after you die. The company says it’s a secure way to give trusted people access to photos, files and messages. To set it up you’ll need an Apple device with a fairly recent operating system — iPhones and iPads need iOS or iPadOS 15.2 and MacBooks needs macOS Monterey 12.1.

For iPhones, go to settings, tap Sign-in & Security and then Legacy Contact. You can name one or more people, and they don’t need an Apple ID or device.

You’ll have to share an access key with your contact. It can be a digital version sent electronically, or you can print a copy or save it as a screenshot or PDF.

Take note that there are some types of files you won’t be able to pass on — including digital rights-protected music, movies and passwords stored in Apple’s password manager. Legacy contacts can only access a deceased user’s account for three years before Apple deletes the account.

Google

Google takes a different approach with its Inactive Account Manager, which allows you to share your data with someone if it notices that you’ve stopped using your account.

When setting it up, you need to decide how long Google should wait — from three to 18 months — before considering your account inactive. Once that time is up, Google can notify up to 10 people.

You can write a message informing them you’ve stopped using the account, and, optionally, include a link to download your data. You can choose what types of data they can access — including emails, photos, calendar entries and YouTube videos.

There’s also an option to automatically delete your account after three months of inactivity, so your contacts will have to download any data before that deadline.

Facebook and Instagram

Some social media platforms can preserve accounts for people who have died so that friends and family can honor their memories.

When users of Facebook or Instagram die, parent company Meta says it can memorialize the account if it gets a “valid request” from a friend or family member. Requests can be submitted through an online form.

The social media company strongly recommends Facebook users add a legacy contact to look after their memorial accounts. Legacy contacts can do things like respond to new friend requests and update pinned posts, but they can’t read private messages or remove or alter previous posts. You can only choose one person, who also has to have a Facebook account.

You can also ask Facebook or Instagram to delete a deceased user’s account if you’re a close family member or an executor. You’ll need to send in documents like a death certificate.

TikTok

The video-sharing platform says that if a user has died, people can submit a request to memorialize the account through the settings menu. Go to the Report a Problem section, then Account and profile, then Manage account, where you can report a deceased user.

Once an account has been memorialized, it will be labeled “Remembering.” No one will be able to log into the account, which prevents anyone from editing the profile or using the account to post new content or send messages.

X

It’s not possible to nominate a legacy contact on Elon Musk’s social media site. But family members or an authorized person can submit a request to deactivate a deceased user’s account.

Passwords

Besides the major online services, you’ll probably have dozens if not hundreds of other digital accounts that your survivors might need to access. You could just write all your login credentials down in a notebook and put it somewhere safe. But making a physical copy presents its own vulnerabilities. What if you lose track of it? What if someone finds it?

Instead, consider a password manager that has an emergency access feature. Password managers are digital vaults that you can use to store all your credentials. Some, like Keeper,Bitwarden and NordPass, allow users to nominate one or more trusted contacts who can access their keys in case of an emergency such as a death.

But there are a few catches: Those contacts also need to use the same password manager and you might have to pay for the service.

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Is there a tech challenge you need help figuring out? Write to us at onetechtip@ap.org with your questions.

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Pediatric group says doctors should regularly screen kids for reading difficulties

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The Canadian Paediatric Society says doctors should regularly screen children for reading difficulties and dyslexia, calling low literacy a “serious public health concern” that can increase the risk of other problems including anxiety, low self-esteem and behavioural issues, with lifelong consequences.

New guidance issued Wednesday says family doctors, nurses, pediatricians and other medical professionals who care for school-aged kids are in a unique position to help struggling readers access educational and specialty supports, noting that identifying problems early couldhelp kids sooner — when it’s more effective — as well as reveal other possible learning or developmental issues.

The 10 recommendations include regular screening for kids aged four to seven, especially if they belong to groups at higher risk of low literacy, including newcomers to Canada, racialized Canadians and Indigenous Peoples. The society says this can be done in a two-to-three-minute office-based assessment.

Other tips encourage doctors to look for conditions often seen among poor readers such as attention-deficit hyperactivity disorder; to advocate for early literacy training for pediatric and family medicine residents; to liaise with schools on behalf of families seeking help; and to push provincial and territorial education ministries to integrate evidence-based phonics instruction into curriculums, starting in kindergarten.

Dr. Scott McLeod, one of the authors and chair of the society’s mental health and developmental disabilities committee, said a key goal is to catch kids who may be falling through the cracks and to better connect families to resources, including quicker targeted help from schools.

“Collaboration in this area is so key because we need to move away from the silos of: everything educational must exist within the educational portfolio,” McLeod said in an interview from Calgary, where he is a developmental pediatrician at Alberta Children’s Hospital.

“Reading, yes, it’s education, but it’s also health because we know that literacy impacts health. So I think that a statement like this opens the window to say: Yes, parents can come to their health-care provider to get advice, get recommendations, hopefully start a collaboration with school teachers.”

McLeod noted that pediatricians already look for signs of low literacy in young children by way of a commonly used tool known as the Rourke Baby Record, which offers a checklist of key topics, such as nutrition and developmental benchmarks, to cover in a well-child appointment.

But he said questions about reading could be “a standing item” in checkups and he hoped the society’s statement to medical professionals who care for children “enhances their confidence in being a strong advocate for the child” while spurring partnerships with others involved in a child’s life such as teachers and psychologists.

The guidance said pediatricians also play a key role in detecting and monitoring conditions that often coexist with difficulty reading such as attention-deficit hyperactivity disorder, but McLeod noted that getting such specific diagnoses typically involves a referral to a specialist, during which time a child continues to struggle.

He also acknowledged that some schools can be slow to act without a specific diagnosis from a specialist, and even then a child may end up on a wait list for school interventions.

“Evidence-based reading instruction shouldn’t have to wait for some of that access to specialized assessments to occur,” he said.

“My hope is that (by) having an existing statement or document written by the Canadian Paediatric Society … we’re able to skip a few steps or have some of the early interventions present,” he said.

McLeod added that obtaining specific assessments from medical specialists is “definitely beneficial and advantageous” to know where a child is at, “but having that sort of clear, thorough assessment shouldn’t be a barrier to intervention starting.”

McLeod said the society was partly spurred to act by 2022’s “Right to Read Inquiry Report” from the Ontario Human Rights Commission, which made 157 recommendations to address inequities related to reading instruction in that province.

He called the new guidelines “a big reminder” to pediatric providers, family doctors, school teachers and psychologists of the importance of literacy.

“Early identification of reading difficulty can truly change the trajectory of a child’s life.”

This report by The Canadian Press was first published Oct. 23, 2024.

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