A breathing aid that can help keep coronavirus patients out of intensive care has been created in under a week.
University College London engineers worked with clinicians at UCLH and Mercedes Formula One to build the device, which delivers oxygen to the lungs without needing a ventilator.
Continuous Positive Airway Pressure (CPAP) devices are already used in hospitals but are in short supply.
China and Italy used them to help Covid-19 patients.
Forty of the new devices have been delivered to ULCH and to three other London hospitals. If trials go well, up to 1,000 of the CPAP machines can be produced per day by Mercedes-AMG-HPP, beginning in a week’s time.
The Medicines and Healthcare products Regulatory Agency (MHRA) has already given its approval for their use.
What do I need to know about the coronavirus?
Professor Rebecca Shipley, Director of UCL Institute of Healthcare Engineering, told the BBC: “Normally medical device development would take years but we’ve done that in days because we went back to a simple existing device and “reverse engineered” it in order to be able to produce them quickly and at scale.”
Reverse engineering means they took apart an existing off-patent CPAP device, copied and improved the design and adapted it for mass production.
Early reports from Lombardy in Italy suggest around 50% of patients given CPAP have avoided the need for invasive mechanical ventilation.
UCLH critical care consultant Professor Mervyn Singer said: “These devices are a halfway house between a simple oxygen mask and invasive mechanical ventilation which requires patients to be sedated.
“They will help to save lives by ensuring that ventilators, a limited resource, are used only for the most severely ill.”
How does CPAP work?
It pushes a steady flow of air-oxygen mix into the mouth and nose of patients.
This is done at pressure which means the lungs remain open and so it increases the amount of oxygen entering them.
This reduces the effort needed to breathe in, especially when the alveoli – the air sacs in the lungs – have collapsed as a result of Covid-19.
Unlike a simple face mask linked to an oxygen supply, CPAP delivers air and oxygen under pressure, so there needs to be a mask creating a tight seal on the patient’s face, over their mouth and nose or a transparent hood over their head.
This is less invasive than a ventilator, for which patients have to be heavily sedated and have a tube inserted into their airway.
But a note of caution was sounded by Duncan Young, Prof of Intensive Care Medicine, University of Oxford, who said: “The use of CPAP machines in patients with contagious respiratory infections is somewhat controversial as any small leaks round the mask could spray droplets of secretions on to attending clinical staff.”
Prof Mervyn Singer said if a tight seal is maintained on the mask or, even better, a helmet is worn, and clinical staff have adequate personal protective equipment (PPE) then this risk would be minimised.
More than 2,000 Covid-19 patients are receiving CPAP on general wards in Lombardy.
Andy Cowell, Managing Director of Mercedes-AMG High Performance Powertrains, said: “The Formula One community has shown an impressive response to the call for support…we have been proud to put our resources at the service of UCL to deliver the CPAP project to the highest standards and in the fastest possible timeframe.”
As well as Mercedes F1, the collaboration also included Oxford Optronix, a small business that has manufactured oxygen monitors for the devices.
Highlights of the day: YMTC said to enter SSD brand business – Digitimes
Highlights of the day: YMTC said to enter SSD brand business
Friday 5 June 2020
China-based NAND flash maker YMTC reportedly is looking to cross into brand SSD business in the third quarter and will focus on supplying the devices to PC makers. Meanwhile, Apple’s new iPhones using OLED panels for 2021 may adopt LTPO backplane in order to reduce their power consumption. With Huawei under the US’ new sanctions, Taiwan’s IC substrate makers have begun turning to strife for more orders from other clients particularly those in the US.
YMTC may unveil own-brand SSDs in 3Q20: China-based Yangtze Memory Technologies (YMTC) reportedly will in third-quarter 2020 launch its own-brand SSDs adopting in-house-developed 64-layer 3D NAND flash, with target outlets including PC OEMs, according to industry sources.
OLED screens of iPhones may adopt LTPO backplanes in 2021, say sources: Apple has yet to introduce its 5G iPhones for 2020, but its supply chain is already developing OLED screens using LTPO (low temperature polycrystalline oxide) backplane technology for next year’s premium iPhone models, according industry sources.
IC substrate makers shifting focus to US clients from Huawei: Taiwan-based IC substrate makers including Unimicron Technology and Na Ya PCB are gearing up to strengthen business ties with US clients seeking to offset expected losses of orders from China’s Huawei/Hisilicon subject to tougher US trade sanctions starting September, according to industry sources.
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Reminder: You Can Download A Free Version Of Clubhouse Games: 51 Worldwide Classics – Nintendo Life
Clubhouse Games: 51 Worldwide Classics is Nintendo’s latest release. If you’re still not sure if this is the right game for you – did you know you can actually try out a free edition that gives you access to four games and local multiplayer?
Yep, if you head on over to the Switch eShop in select regions, you can download it right now. The four games included are Dominos, Four-in-a-Row, President, and Slot Cars. Apart from local multiplayer options, you can also play each game by yourself. Here’s a description along with the Japanese trailer:
About the Guest Edition:
This trial version of 51 Worldwide Games includes 4 games that you can take on the go to play anytime, anywhere. You can play the games contained here in Local Play with other players who have the Guest Edition! If your friends download the Guest Edition, up to 4 players can join in a game of dominoes or president. If someone has the full version, you can use Local Play to join in any of the multiplayer games.
Will you be trying out this free edition, or jumping straight into the full game? Leave a comment down below.
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