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Got a cold? It could protect you from other viruses — but only for a bit

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Infectious disease experts say having one virus like a common cold could keep others at bay, as each bug effectively takes turns over the fall and winter.

Respiratory syncytial virus, or RSV, infections are stabilizing across the country and flu is picking up sharply, according to the Public Health Agency of Canada.

Canadians are mingling and travelling freely again. The mixing of people with each other gives scientists a rare opportunity to watch how the different respiratory pathogens we carry interact after a pandemic.

Until now, most virus research has focused on just a single pathogen at a time, whether in an individual patient or a whole population.

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Here’s a look at the early science into why we likely won’t see multiple viruses hitting adults at the same time — and who may be more vulnerable to a double- or triple-whammy.

Multiple viruses may not hit adults at the same time but kids could face a double-whammy or worse. Scientists are exploring how and when viruses interfere with one another. (BSIP/UIG/Getty)

Virus triggers immune defence

Though the idea of viruses interfering with one another has been discussed since the 1960s, the 2009 H1N1 influenza pandemic gave scientists some further clues about it.

Dr. Guy Boivin, a virologist and professor of pediatrics at Laval University in Quebec City, wrote a commentary earlier this year reviewing the evidence on viral interference — competition between respiratory viruses interfering or blocking each other’s spread.

“It was notable that the [H1N1 flu] pandemic virus emerged in France two to three months after its emergence in the other European countries,” Boivin said. “That was related to a rhinovirus outbreak at that time. This small epidemic of rhinoviruses delayed the pandemic H1N1 virus in France.”

Rhinovirus is a type of a common cold virus.

When it comes to waves of different respiratory infections like COVID, RSV and flu circulating in Canada, Boivin said he expects some overlap. But he also thinks it’s unlikely they will all peak at the same time, because catching one bug can offer short-term protection against other viruses.

 

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Dr. Ellen Foxman, an immunologist at the Yale School of Medicine in New Haven, Conn., studies antiviral defences at her lab, including how viral interference happens.

“Having one virus activates antiviral defences in your body,” Foxman said. “That can protect against other viruses too, at least for a short span of time.”

Foxman said it’s possible that having one infection makes you less likely to get another at the same time. For instance, if human airway tissues are infected with rhinovirus and then the H1N1 flu is introduced a few days later, the influenza virus won’t grow.

“It was because the defences that the tissue turned on in response to the rhinovirus also protected against the flu,” Foxman said.

She’s currently looking at interference between the virus that causes COVID-19 and other viruses in human airway samples at her lab.

An exterior view of people walking by a hospital in France in 2009 during the H1N1 flu pandemic.
A view of the Bichat Hospital where the French Health ministry said a patient was treated for a confirmed case of H1N1 pandemic flu in May 2009. Scientists say another virus seemed to suppress H1N1 initially in France. (Benoit Tessier/Reuters)

Short-lived protection

Foxman said the lining of our airways take on an antiviral defensive state when they sense an invader.

The guard defence is one of several layers of protection in the immune system. One is called interferon: a family of proteins produced by the body’s immune system in response to an invading viral infection.

As the name implies, interferon interferes with or blocks the ability of a virus to accomplish its raison d’être of making copies of itself.

Instead, interferon summons immune cells to the site of the invasion so they can take up arms against the threat.

But interferon doesn’t stay turned on for long, cautioned Dr. Allison McGeer, an infectious diseases specialist at Sinai Health System in Toronto.

“It’s not an effect with most viruses and it’s not a big effect,” McGeer said.

Dr. Allison McGeer, an infectious diseases specialist at Sinai Health System in Toronto, says the effect of viral interference is small. (Evan Mitsui/CBC)

The opposite can also happen. Some people get double or co-infections — two or more bugs at the same time.

Why that’s the case isn’t well understood and the degree to which it happens is just starting to be explored. 

McGeer said co-infections happen “not infrequently” among kids admitted to the hospital.

Baby’s multiple infections at once

Emilie Doré’s six-week-old son, Diego, was one of them. “My mom instincts were telling me that it was a bad cold on a baby who is just too little, too young,” Doré recalled.

A baby with hospital tubes.
Baby Diego was hospitalized at Montreal Children’s Hospital for four days with multiple respiratory infections. (Submitted by Emilie Doré)

Doré was on the lookout for symptoms in the infant after her two-year-old daughter fell sick. First the baby had a little congestion and a cough followed by lethargy and fever.

“I would say the most upsetting and worrying time was when he had to be connected to oxygen because he was having difficulty breathing,” the Montreal mother said.

When he wasn’t getting better, Diego had a lumbar puncture or spinal tap procedure. The tests suggested he had RSV, rhinovirus and enterovirus, another common cold virus, as well as possibly meningitis.

He recovered after four days in hospital and is now eight weeks old.

A young baby wearing a T-shirt and cap.
Baby Diego has now recovered. (Submitted by Emilie Dore)

Virologists say at a population level, other factors, such as human behaviour of different age groups, population immunity, environmental conditions like temperature and humidity and what’s happened during the COVID-19 pandemic also influence the triple threat of viral spread.

Separate waves of each virus may still sicken individuals and increase demand on emergency departments and primary care services at a time they’re struggling with staffing shortages and backlogs.

Dr. Gerald Evans, chair of infectious diseases at Queen’s University and Kingston Health Sciences Centre, said when people in hospital are tested for respiratory infections now, three viruses can appear.

“We are starting to pick up a small signal that people can get infected with both flu and with COVID, and certainly in children we see flu and RSV popping up,” Evans said.

“So the impact of that coinfection we’re still going to have to figure out. We are seeing it. It’s small numbers.”

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It's possible to rely on plant proteins without sacrificing training gains, new studies say – The Globe and Mail

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At the 1936 Olympics in Berlin, a scientist named Paul Schenk surveyed the eating habits of top athletes from around the world. The Canadians reported plowing through more than 800 grams of meat per day on average; the Americans were downing more than two litres of milk daily.

While there have been plenty of changes in sports nutrition since then, the belief that meat and dairy are the best fuel for building muscle persists. These days, though, a growing number of athletes are interested in reducing or eliminating their reliance on animal proteins, for environmental, ethical or health reasons. A pair of new studies bolsters the case that it’s possible to rely on plant proteins without sacrificing training gains, as long as you pick your proteins carefully.

The standard objection to plant proteins is that they don’t have the right mix of essential amino acids needed to assemble new muscle fibres. Unlike animal proteins, most plant proteins are missing or low in at least one essential amino acid.

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In particular, there’s one specific amino acid, leucine, that seems to play a special role in triggering the synthesis of new muscle. It’s particularly abundant in whey, one of the two proteins (along with casein) found in milk. That’s why whey protein is the powdered beverage of choice in gyms around the world, backed by decades of convincing research, which was often funded by the dairy industry.

But one of the reasons whey looks so good may be that we haven’t fully explored the alternatives. A 2018 study by Luc van Loon of the University of Maastricht in the Netherlands, for example, tested nine vegetable proteins including wheat, hemp, soy, brown rice, pea and corn. To their surprise, they found that corn protein contains 13.5 per cent leucine – even more than whey.

Based on that insight, van Loon decided to pit corn against milk in a direct test of muscle protein synthesis. Volunteers consumed 30 grams of one of the proteins; a series of blood tests and muscle biopsies were collected over the next five hours to determine how much of the ingested protein was being turned into new muscle fibres. The results, which appeared in the journal Amino Acids, were straightforward: Despite all the hype about whey, there was no discernible difference between them.

A second study, this one published in Medicine & Science in Sports & Exercise by a team led by Benjamin Wall of the University of Exeter in Britain, had similar findings. Instead of corn, it used a mix of 40 per cent pea, 40 per cent brown rice and 20 per cent canola proteins. Since different plants have different amino acids profiles, mixing complementary proteins has long been suggested as a way overcoming the deficiencies of any single plant protein. Sure enough, the protein blend triggered just as much new muscle synthesis as whey.

On the surface, the message from these studies is straightforward: Plant proteins are – or at least can be – as effective as even the best animal proteins for supporting muscle growth. There are a few caveats to consider, though. One is that the studies used isolated protein powders rather than whole foods. You would need nearly nine cobs of corn to get the 30 grams of protein used in van Loon’s study, compared to just three-and-a-half cups of milk.

Another is that plants are generally harder to digest, meaning that not all the amino acids will be usable. That may not be a problem for healthy young adults consuming 30 grams of protein at once, which is enough to trigger a near-maximal muscle response. But for older people, who tend to have blunted muscle-building responses to protein, or in situations where you’re getting a smaller dose of protein, the details of protein quality may become more important.

Of course, the effectiveness of plant proteins won’t be news to notable plant-based athletes such as ultrarunner Scott Jurek or basketball star Chris Paul – but it’s encouraging to see the science finally begin to catch up.

Alex Hutchinson is the author of Endure: Mind, Body, and the Curiously Elastic Limits of Human Performance. Follow him on Threads @sweat_science.

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See how chicken farmers are trying to stop the spread of bird flu – Fox 46 Charlotte

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CLOVER, S.C. (QUEEN CITY NEWS) — Poultry farmers across the Carolinas aren’t taking any chances.  Many are turning to strict protocols as another wave of bird flu continues to threaten the chicken population across the country. 

Since 2022, it is estimated more than 90 million birds have either died from the virus or were killed to prevent further spread in the U.S. 

“We try to make them the happiest as possible. We always say a happy chicken is a tasty chicken,” owner of Eden Farms Adam Shumate said. 

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With their happiness in mid, Shumate also wants to keep his chickens alive and healthy. On his farm in Clover, he has implemented protocols to minimize a potential bird flu outbreak.  

“We want to be prepared,” he said. “We feel like the things that we can do to prevent it first is the best case because we don’t want to start from scratch with a whole new flock.”  

Because bird flu is commonly spread through bird droppings, Shumate is limiting the number of people coming into contact with his flocks. He says this would minimize the chances of someone walking onto the property with bird droppings on the bottoms of their shoes. 

On top of monitoring the chickens closely, Shumate and his staff are constantly cleaning their equipment, including what they wear on their feet.   

“We have specific shoes that are just for working with the flock and for when we are taking care of them,” Shumate said. 

Other farmers, like Holly Burrell, haven’t let a visitor step foot near her hens in Gastonia for more than two years. 

No visitors or outside cars are welcomed, and her chickens are separated in what she calls “tent cities.” 

“We don’t want to do that because we want them to live their best life,” Burrell said in a 2022 interview with Queen City News. 

Recently, health officials have detected bird flu in other animals like seals, squirrels and dolphins. 

Earlier this month, bird flu was detected in one of the state’s dairy cow herds. While concerning, state health officials say the overall risk to the general public remains low. 

“I’ve not heard of any cases, zero cases of people being affected by this virus associated with food consumption, milk consumption with egg consumption… any of these products we’re getting from farm animals is not really been associated with any human risk at this point,” said Dr. Michael Martin, director of the Veterinary Division at the N.C. Department of Agriculture and Consumer Services. 

As of March 28, at least 80 birds in North Carolina were detected with the virus. Back in York County, Shumate says it all starts with the individual farms. 

“When it comes to wildlife and things that that, there is only so much that you can do is be observant,” Shumate said. “Keep a healthy flock that way they can find off the infections that may come about.” 

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CFIA Monitoring for Avian Influenza in Canadian Dairy Cattle After US Discoveries – Morning Ag Clips –

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From the field to your inbox, the Weekend Edition of the Morning Ag Clips features stories, trends, and unique perspectives from the farming community. This laid-back edition is great for anyone looking for a fun weekend read.

Morning Ag Clips. All ag. All the time.

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