A worker disinfects a mosque in Istanbul as part of city-wide efforts to contain the spread of COVID-19.Credit: Chris McGrath/Getty
How is the coronavirus spreading around the world?
The coronavirus emerged in Wuhan, a city of 11 million people in China’s Hubei province, in late 2019. Cases of the disease it causes, COVID-19, grew by several thousand per day in China in late January and early February, the peak of the epidemic there.
The number of infections appearing each day has since plummeted in China, owing in large part to containment efforts, but the outbreak is now a global pandemic. Large outbreaks in South Korea, Iran, Italy and elsewhere have propelled a spike in international cases across more than 150 countries.
Source: World Health Organization
The total number of confirmed cases outside China has now eclipsed those inside the country, and on 13 March, the World Health Organization’s director-general Tedros Adhanom Ghebreyesus, said Europe had become the epicentre of the pandemic.
How does COVID-19 compare to other diseases?
Current estimates of COVID-19’s case fatality rate — a measure of the proportion of infected people who eventually die — suggest that the coronavirus is less deadly than the pathogens behind other large-scale outbreaks, such as of SARS (severe acute respiratory syndrome), MERS (Middle East respiratory syndrome) and Ebola.
But the infection also seems to spread more easily than other diseases, including seasonal influenza. Calculations of the virus’s basic reproduction number, or R0 — the number of people on average one infected person will pass the virus to — suggest a range of 2–2.5.
Like the case fatality rate, R0 is an estimate that can vary considerably by location, with age group, and over time, and that is likely to be revised. It is calculated using models that take into account how long an infected person remains contagious, the likelihood of them infecting contacts and how often they come into contact with other people.
How fast are researchers publishing new coronavirus research?
The outbreak has prompted an explosion of research on the coronavirus and the disease that it causes. To get an estimate of the scale of research activity, Nature searched for studies using the terms ‘novel coronavirus’, ‘ncov’, ‘COVID-19’ and ‘SARS-CoV-2’ on the bioRxiv, medRxiv, ChemRxiv and ChinaXiv servers, as well as compiling publications listed by the WHO, and on Google Scholar. As of 12 March there had been around 900 papers, preprints and preliminary reports related to coronavirus.
The research covers a range of subjects, including the structure of the virus; how it spreads in different communities; clinical features of the disease; potential drug targets; how effective quarantine measures are; and the psychological effects of the outbreak on health workers. At least 20 of the preprints that were shared early in the outbreak have since been published in peer-reviewed journals.
Researchers have also shared genomic data on the virus using online platforms such as GISAID and GenBank, and several clinical trials are under way for potential vaccines or treatments. Nature’s analysis does not include these reports or data. Neither does it include studies published in languages other than English, for example in Chinese-language journals. It is therefore likely to underestimate the total body of work on the coronavirus so far.
How have travel restrictions affected carbon emissions and air quality?
China’s efforts to control the outbreak seem to have curbed energy consumption — and air pollution. Satellite data collected by NASA and the European Space Agency show a sharp reduction in atmospheric levels of nitrogen dioxide (NO2), which is produced during fossil fuel combustion, across the country.
Source: NASA Earth Observatory
Each year, industrial activity typically drops off as businesses and factories close for celebrations of the lunar New Year, which this year began on 25 January. This usually causes a brief dip in levels of NO2. “Normally, the pollution levels pick back up after 7–10 days, but that has not happened this year,” says Fei Liu, an atmospheric scientist at NASA’s Goddard Space Flight Center in Greenbelt, Maryland. A preliminary analysis suggests that NO2 pollution after the lunar New Year was around 10–30% lower this year than during the same period in previous years. A similar trend of declining NO2 pollution has also been documented in northern Italy — where cities remain on lockdown — using data from the European Space Agency’s Sentinel-5P satellite.
Ongoing efforts to contain the coronavirus have suppressed China’s industrial activity by 15–40%, according to an analysis by the Centre for Research on Energy and Clean Air in Helsinki. Coal consumption hit a four-year low in February, and oil refining fell by more than one-third. Overall, the centre’s analysis suggests that China’s carbon emissions have dropped by more than 25% as a result of the ongoing efforts to contain the coronavirus.
How does the current pandemic compare to the 2003 SARS outbreak?
The COVID-19 coronavirus has, from the beginning, drawn comparisons to the 2002–03 outbreak of SARS. Both originated in China before spreading around the world. Both were identified as new coronaviruses, deadlier than the handful of related viruses that cause common colds. The SARS coronavirus was found to have jumped to people from civet cats that had picked it up from bats. The COVID-19 virus, called SARS-CoV-2, is also thought to have come from bats, either directly or through an as-yet unidentified mammal. Both viruses caused chaos and economic disaster. But the two outbreaks have progressed very differently, especially in the speed and extent of spread.
The SARS outbreak went on for three months before being identified as a distinct disease. Then, for nearly two more months, it was a disease in search of a pathogen: the identification and genomic sequencing of the virus itself largely came from researchers outside China.
By contrast, three weeks after the first known case of the disease now known as COVID-19, China had notified the WHO of a spike in cases of a pneumonia-like disease. Two weeks after that, the coronavirus had been isolated, genetically sequenced, and a diagnostic test developed, giving China the tools it needed to launch one of the greatest infectious-disease containment efforts the world has ever seen.
The COVID-19 virus, although not as lethal as SARS, has proved much more pervasive. It took less than two months from the discovery of the first infection for the number of confirmed cases to pass the total that SARS reached over several months. And in three months, COVID-19 has killed more than five times as many people as SARS.
HALIFAX – The Nova Scotia government says it could be months before it reveals how many people are on the wait-list for a family doctor.
The head of the province’s health authority told reporters Wednesday that the government won’t release updated data until the 160,000 people who were on the wait-list in June are contacted to verify whether they still need primary care.
Karen Oldfield said Nova Scotia Health is working on validating the primary care wait-list data before posting new numbers, and that work may take a matter of months. The most recent public wait-list figures are from June 1, when 160,234 people, or about 16 per cent of the population, were on it.
“It’s going to take time to make 160,000 calls,” Oldfield said. “We are not talking weeks, we are talking months.”
The interim CEO and president of Nova Scotia Health said people on the list are being asked where they live, whether they still need a family doctor, and to give an update on their health.
A spokesperson with the province’s Health Department says the government and its health authority are “working hard” to turn the wait-list registry into a useful tool, adding that the data will be shared once it is validated.
Nova Scotia’s NDP are calling on Premier Tim Houston to immediately release statistics on how many people are looking for a family doctor. On Tuesday, the NDP introduced a bill that would require the health minister to make the number public every month.
“It is unacceptable for the list to be more than three months out of date,” NDP Leader Claudia Chender said Tuesday.
Chender said releasing this data regularly is vital so Nova Scotians can track the government’s progress on its main 2021 campaign promise: fixing health care.
The number of people in need of a family doctor has more than doubled between the 2021 summer election campaign and June 2024. Since September 2021 about 300 doctors have been added to the provincial health system, the Health Department said.
“We’ll know if Tim Houston is keeping his 2021 election promise to fix health care when Nova Scotians are attached to primary care,” Chender said.
This report by The Canadian Press was first published Sept. 11, 2024.
ST. JOHN’S, N.L. – Newfoundland and Labrador‘s chief medical officer is monitoring the rise of whooping cough infections across the province as cases of the highly contagious disease continue to grow across Canada.
Dr. Janice Fitzgerald says that so far this year, the province has recorded 230 confirmed cases of the vaccine-preventable respiratory tract infection, also known as pertussis.
Late last month, Quebec reported more than 11,000 cases during the same time period, while Ontario counted 470 cases, well above the five-year average of 98. In Quebec, the majority of patients are between the ages of 10 and 14.
Meanwhile, New Brunswick has declared a whooping cough outbreak across the province. A total of 141 cases were reported by last month, exceeding the five-year average of 34.
The disease can lead to severe complications among vulnerable populations including infants, who are at the highest risk of suffering from complications like pneumonia and seizures. Symptoms may start with a runny nose, mild fever and cough, then progress to severe coughing accompanied by a distinctive “whooping” sound during inhalation.
“The public, especially pregnant people and those in close contact with infants, are encouraged to be aware of symptoms related to pertussis and to ensure vaccinations are up to date,” Newfoundland and Labrador’s Health Department said in a statement.
Whooping cough can be treated with antibiotics, but vaccination is the most effective way to control the spread of the disease. As a result, the province has expanded immunization efforts this school year. While booster doses are already offered in Grade 9, the vaccine is now being offered to Grade 8 students as well.
Public health officials say whooping cough is a cyclical disease that increases every two to five or six years.
Meanwhile, New Brunswick’s acting chief medical officer of health expects the current case count to get worse before tapering off.
A rise in whooping cough cases has also been reported in the United States and elsewhere. The Pan American Health Organization issued an alert in July encouraging countries to ramp up their surveillance and vaccination coverage.
This report by The Canadian Press was first published Sept. 10, 2024.
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