Connect with us

Business

There’s no ‘best’ vaccine, expert says as Canada OKs AstraZeneca shots – Globalnews.ca

Published

 on


Vaccines from Moderna, Pfizer-BioNTech and AstraZeneca-Oxford have now been approved in Canada.  While Canadians may not get a choice about which COVID-19 vaccine to take, all three offer protection against severe illness, according to experts.

“All of these vaccines are good,” Dr. Bradly Wouters, executive vice-president of science and research at the University Health Network told Global News Friday.

Read more:
What are the differences between Canada’s approved COVID-19 vaccines? Here’s what we know

Available data shows all these three vaccines have the “ability to impact hospitalization” and offer “protection against severe illness,” he said.

Which vaccine is the best?

There’s no “best vaccine” option.

Whichever vaccine is available first, “it’s going to protect you,” Wouters said.

Story continues below advertisement

Parts of the world are already facing which-is-best challenges. Astrazeneca’s vaccine for instance, was cleared for use in Britain and Europe after data suggested that it was about 70 per cent effective.

Italy’s government recently decided to reserve Pfizer and Moderna shots for the elderly and designate the Astrazeneca vaccine for younger, at-risk workers, sparking protests.

“Right now, it’s not vaccine against vaccine, it’s vaccine against virus,” Dr. Nirav Shah, director of the Maine Center for Disease Control and Prevention, recently told The Associated Press.

Wouters reiterated a similar notion.

“In a pandemic, you need fast results,” he noted and the “priority is to ensure everyone gets vaccinated” and not “debate over which vaccine is better.”

“Each trial involves different people in different places,” he said, and while many may be making comparisons between vaccines from the results of different Phase 3 trials, “such comparisons are misleading,” he said.

After Pfizer and Moderna, AstraZeneca is the third shot officially authorized in the country.


Click to play video 'Health Canada official explains how AstraZeneca’s COVID-19 vaccine works'



0:59
Health Canada official explains how AstraZeneca’s COVID-19 vaccine works


Health Canada official explains how AstraZeneca’s COVID-19 vaccine works

The two doses of the Pfizer and Moderna shots were found to be about 95 per cent effective against the virus as compared to the AstraZeneca shots that stand at 62 per cent in preventing symptomatic cases.

Story continues below advertisement

However, Wouters said they will all work “as effectively as possible as long as combined with mask-wearing, handwashing and social distancing.”

[ Sign up for our Health IQ newsletter for the latest coronavirus updates ]

“We must continue to follow public health guidelines, being cautious until positive cases, hospitalizations and deaths are significantly reduced nationwide,” he said.

Following Canada’s approval of AstraZeneca’s COVID-19 vaccine Friday, Procurement Minister Anita Anand cautioned against deliberation over “the sort of good or bad” vaccines.


Click to play video 'Coronavirus: Canada secures 2M doses of CoviShield vaccine, to arrive in weeks'



2:08
Coronavirus: Canada secures 2M doses of CoviShield vaccine, to arrive in weeks


Coronavirus: Canada secures 2M doses of CoviShield vaccine, to arrive in weeks

“If there is a vaccine and it’s been authorized by Health Canada, it means that it’s met standards,” Anand said during a press conference Friday.

AstraZeneca shots may not seem equal to its opponents at first glance but “these vaccines do have a use,” she said.

“We have real-world evidence from Scotland and the U.K. for people that have been dosed that have been over 80, and that has shown a significant drop in hospitalizations, to the tune of 84 per cent,” she said.

Story continues below advertisement

“The idea is to have a suite of vaccines that are available. I think Canada is hungry for vaccines, we’re putting more on the buffet table to be used.”

Standards of efficacy

Speaking of the “standards of effectiveness,” Anand said vaccines “should meet at least 50 per cent.”

“If we compare that to the influenza viruses that we authorize every year, if you look back, for example, just to last year, the effectiveness of the flu vaccine against the most common strain was about 64 per cent, across to the next common strain was about 54 per cent,” she said.

As more information becomes available from real-world use, “the efficacy” of the AstraZeneca vaccine might prove to “be much higher,” Anand added.

Read more:
Canada approves AstraZeneca’s COVID-19 vaccine

Considering all the five vaccines that are currently under review, including the Novavax and Johnson & Johnson shots, Anand emphasized that nobody has died so far from “adverse effects” of these vaccines.

“If you look across all the clinical trials of the tens of thousands of people that were involved, the number of cases of people that died from COVID-19 that got vaccine was zero. The number of people that were hospitalized because their COVID-19 disease was so severe was zero. The number of people that died because of an adverse event or an effect of the vaccine was zero,” she said.

Story continues below advertisement

The idea is “to prevent” serious illness, hospitalizations and “of course prevent death,” Anand said.

Storage and distribution

Compared to the other vaccines, the AstraZeneca shot is also easier to administer.

The vaccine can be stored, transported and handled at normal refrigerated conditions (2 to 8 C/36 to 46 F) for at least six months and administered within existing health-care settings.


Click to play video 'Cold storage of COVID-19 vaccine complicates rollout'



2:54
Cold storage of COVID-19 vaccine complicates rollout


Cold storage of COVID-19 vaccine complicates rollout – Dec 8, 2020

The Moderna and Pfizer options, meanwhile, must be stored at subzero temperatures until they’re ready to be used, at -4 F and -94 F, respectively.

This is “something we need to take into account,” Dr. Howard Njoo, Canada’s deputy chief public health officer, said during a press conference Friday.

Story continues below advertisement

He said the onboarding of the AstraZeneca vaccine is “another tool in our toolbox.”

“Following the approval of Health Canada, the efficacy stands at 62 per cent, but we have to look at the entire profile of each vaccine because this vaccine is easier to administer than Pfizer and Moderna, so this is something we need to take into account,” he said.

— With files from The Associated Press

© 2021 Global News, a division of Corus Entertainment Inc.

Let’s block ads! (Why?)



Source link

Continue Reading

Business

U.K. advises limiting AstraZeneca in under-30s amid clot worry

Published

 on

LONDON —
British authorities recommended Wednesday that the AstraZeneca COVID-19 vaccine not be given to adults under 30 where possible because of strengthening evidence that the shot may be linked to rare blood clots.

The recommendation came as regulators both in the United Kingdom and the European Union emphasized that the benefits of receiving the vaccine continue to outweigh the risks for most people — even though the European Medicines Agency said it had found a “possible link” between the shot and the rare clots. British authorities recommended that people under 30 be offered alternatives to AstraZeneca. But the EMA advised no such age restrictions, leaving it up to its member-countries to decide whether to limit its use.

Several countries have already imposed limits on who can receive the vaccine, and any restrictions are closely watched since the vaccine, which is cheaper and easier to store than many others, is critical to global immunization campaigns and is a pillar of the UN-backed program known as COVAX that aims to get vaccines to some of the world’s poorest countries.

“This is a course correction, there’s no question about that,” Jonathan Van-Tam, England’s deputy chief medical officer, said during a press briefing. “But it is, in a sense, in medicine quite normal for physicians to alter their preferences for how patients are treated over time.”

Van-Tam said the effect on Britain’s vaccination timetable — one of the speediest in the world — should be “zero or negligible,” assuming the National Health Service receives expected deliveries of other vaccines, including those produced by Pfizer and Moderna.

EU and U.K. regulators held simultaneous press conferences Wednesday afternoon to announce the results of investigations into reports of blood clots that sparked concern about the rollout of the AstraZeneca vaccine.

The EU agency described the clots as “very rare” side effects. Dr Sabine Straus, chair of EMA’s Safety Committee, said the best data is coming from Germany where there is one report of the rare clots for every 100,000 doses given, although she noted far fewer reports in the U.K. Still, that’s less than the clot risk that healthy women face from birth control pills, noted another expert, Dr. Peter Arlett.

The agency said most of the cases reported have occurred in women under 60 within two weeks of vaccination — but based on the currently available evidence, it was not able to identify specific risk factors. Experts reviewed several dozen cases that came mainly from Europe and the U.K., where around 25 million people have received the AstraZeneca vaccine.

“The reported cases of unusual blood clotting following vaccination with the AstraZeneca vaccine should be listed as possible side effects of the vaccine,” said Emer Cooke, the agency’s executive director. “The risk of mortality from COVID is much greater than the risk of mortality from these side effects.”

Arlett said there is no information suggesting an increased risk from the other major COVID-19 vaccines.

The EMA’s investigation focused on unusual types of blood clots that are occurring along with low blood platelets. One rare clot type appears in multiple blood vessels and the other in veins that drain blood from the brain.

While the benefits of the vaccine still outweigh the risks, that assessment is “more finely balanced” among younger people who are less likely to become seriously ill with COVID-19, the U.K’s Van-Tam said.

“We are not advising a stop to any vaccination for any individual in any age group,” said Wei Shen Lim, who chairs Britain’s Joint Committee on Vaccination and Immunization. “We are advising a preference for one vaccine over another vaccine for a particular age group, really out of the utmost caution rather than because we have any serious safety concerns.”

In March, more than a dozen countries, mostly in Europe, suspended their use of AstraZeneca over the blood clot issue. Most restarted — some with age restrictions — after the EMA said countries should continue using the potentially life-saving vaccine.

Britain, which relies heavily on AstraZeneca, however, continued to use it.

The suspensions were seen as particularly damaging for AstraZeneca because they came after repeated missteps in how the company reported data on the vaccine’s effectiveness and concerns over how well its shot worked in older people. That has led to frequently changing advice in some countries on who can take the vaccine, raising worries that AstraZeneca’s credibility could be permanently damaged, spurring more vaccine hesitancy and prolonging the pandemic.

Dr. Peter English, who formerly chaired the British Medical Association’s Public Health Medicine Committee, said the back-and-forth over the AstraZeneca vaccine globally could have serious consequences.

“We can’t afford not to use this vaccine if we are going to end the pandemic,” he said.

In some countries, authorities have already noted hesitance toward the AstraZeneca shot.

“People come and they are reluctant to take the AstraZeneca vaccine, they ask us if we also use anything else,” said Florentina Nastase, a doctor and co-ordinator at a vaccination centre in Bucharest, Romania. “There were cases in which people (scheduled for the AstraZeneca) didn’t show up, there were cases when people came to the centre and saw that we use only AstraZeneca and refused (to be inoculated).”

Meanwhile, the governor of Italy’s northern Veneto region had said earlier Wednesday that any decision to change the guidance on AstraZeneca would cause major disruptions to immunizations — at a time when Europe is already struggling to ramp them up — and could create more confusion about the shot.

“If they do like Germany, and allow Astra Zeneca only to people over 65, that would be absurd. Before it was only for people under 55. Put yourself in the place of citizens, it is hard to understand anything,” Luca Zaia told reporters.

The latest suspension of AstraZeneca came in Spain’s Castilla y Leon region, where health chief Veronica Casado said Wednesday that “the principle of prudence” drove her to put a temporary hold on the vaccine that she still backed as being both effective and necessary.

French health authorities had said they, too, were awaiting EMA’s conclusions, as were some officials in Asia.

On Wednesday, South Korea said it would temporarily suspend the use of AstraZeneca’s vaccine in people 60 and younger. In that age group, the country is only currently vaccinating health workers and people in long-term care settings.

The Korea Disease Control and Prevention Agency said it would also pause a vaccine rollout to school nurses and teachers that was to begin on Thursday, while awaiting the outcome of the EMA’s review.

But some experts urged perspective. Prof Anthony Harnden, the deputy chair of Britain’s vaccination committee, said that the program has saved at least 6,000 lives in the first three months and will help pave the way back to normal life.

“What is clear it that for the vast majority of people the benefits of the Oxford AZ vaccine far outweigh any extremely small risk,” he said. “And the Oxford AZ vaccine will continue to save many from suffering the devastating effects that can result from a COVID infection.”

Source: – CTV News

Source link

Continue Reading

Business

Facebook downplays ‘old’ breach exposing info on 533 million users

Published

 on

Facebook is downplaying the significance of a data breach that saw the personal information of 533 million of its users accessed online, saying the information is old and the vulnerability that was exploited was closed almost two years ago.

Over the weekend, Business Insider reported that personal information of Facebook users in 106 countries was found on a low-level hacking forum, free of charge. Cybercrime intelligence firm Hudson Rock calculated that almost 3.5 million Canadians were included.

Information included names, phone numbers, locations, birth dates, email addresses and other identifying details. No financial or payment information was accessed, Facebook said.

In a statement on its website Tuesday the social media giant said the information was gathered via a vulnerability the company fixed almost two years ago, and disputed that it was a hack.

Data scraped, not hacked: Facebook

“It is important to understand that malicious actors obtained this data not through hacking our systems but by scraping it from our platform prior to September 2019,” said product management director Mike Clark.

Scraping refers to the act of gathering information that is already out there but somewhat hidden on public databases.

The company said whoever collected and assembled the data did so by abusing the contact importing service, which allows users to find other people in their network on Facebook.

Facebook said whoever did it seems to have uploaded a large set of phone numbers to see which ones matched Facebook users.

David Masson, director of enterprise security at cybersecurity firm Darktrace, says the information has likely been out there and spread widely for a while, before being outed recently.

“It’s been on the Web for quite a while, probably for sale to people,” he said. “But now somebody’s just offered it up for free.”

Building a profile

Greg Wolfond, CEO of data security firm SecureKey, said that in a vacuum, much of the information taken can seem innocuous and harmless, but when taken together can be very dangerous.

“What the hackers do is they try and get little bits of data about you in this case something like your phone number,” he told CBC News in an interview. They can then combine that with other bits of information — an address, a full name — and start building a profile.

What’s most dangerous is once they have gathered enough to attempt to gain access to a cellphone account. With the right combination of information, a telecom company may allow someone walking in to port the account number to a new phone.

 

Cybersecurity expert David Masson with Darktrace says Facebook users shouldn’t assume the company’s size and scope make them better at fending off attacks. (Darktrace)

 

“They take over your phone, and within minutes of taking over your phone, they’re trying to get into your bank account, to get into your Facebook account, your Google account, whatever you use that phone as your recovery for,” he said.

Typically, consumers are urged to fight data theft by doing things like changing passwords frequently, and making the complex. But those things are of little use when companies claim the right to reams of data about their users, and promise to keep it safe.

“Empowering individuals to share their data and putting a responsibility on parties that have the data to keep it secure,
is super important,” he said.

Not Facebook’s first user-info incident

Although the company is downplayed in the incident, it is far from the company’s first misstep with user info.

In 2018, the social media giant disabled a feature that allowed users to search for one another via phone number following revelations that the political firm Cambridge Analytica had accessed information on up to 87 million Facebook users without their knowledge or consent.

In December 2019, a Ukrainian security researcher reported finding a database with the names, phone numbers and unique user IDs of more than 267 million Facebook users — nearly all U.S.-based — on the open internet.

Spark15:32Digital security expert shares tips on how to protect your data while working remotely 

During the COVID-19 pandemic, we are spending more of our time at home online than ever before – and according to Citizen Lab’s John Scott-Railton, this makes us vulnerable to privacy and security threats. 15:32

Facebook says it will “continue aggressively go after malicious actors who misuse our tools,” and touted its dedicated team focused on this work” but  Masson says users shouldn’t make the mistake of assuming that the company’s size and scope somehow make them better equipped to keep user data safe.

“It doesn’t matter how big or sophisticated you are, they can be attacked,” he said.

Like many breaches, this one was only discovered long after the fact, and that’s because the technology company’s use isn’t keeping up with the ones the hackers are using.

“There are better technologies that actually work on what happens once the bad guys get inside your network rather than when they’re banging on the door outside. So people [have] got to realize this will happen again.

Source: – CBC.ca

Source link

Continue Reading

Business

Before you continue

Published

 on



Google uses cookies and data to:

  • Deliver and maintain services, like tracking outages and protecting against spam, fraud and abuse
  • Measure audience engagement and site statistics to understand how our services are used

If you agree, we’ll also use cookies and data to:

  • Improve the quality of our services and develop new ones
  • Deliver and measure the effectiveness of ads
  • Show personalised content, depending on your settings
  • Show personalised or generic ads, depending on your settings, on Google and across the web

For non-personalised content and ads, what you see may be influenced by things like the content that you’re currently viewing and your location (ad serving is based on general location). Personalised content and ads can be based on those things and your activity, like Google searches and videos that you watch on YouTube. Personalised content and ads include things like more relevant results and recommendations, a customised YouTube homepage, and ads that are tailored to your interests.

Click ‘Customise’ to review options, including controls to reject the use of cookies for personalisation and information about browser-level controls to reject some or all cookies for other uses. You can also visit g.co/privacytools at any time.

Let’s block ads! (Why?)



Source link

Continue Reading

Trending