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Vaccine against infection in bees approved in Canada – CTV News

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The first vaccine for bees has been approved for use in Canada.

The Canadian Food Inspection Agency has conditionally licensed an oral vaccine to protect honey bees against a disease called American foulbrood, which can wipe out entire colonies if not treated.

The manufacturer, U.S.-based Dalan Animal Health, announced the Canadian approval in a news release on Oct. 16.

The vaccine can be used in Canada “under veterinary supervision,” the food inspection agency said in an email.

American foulbrood is caused by the Paenibacillus larvae bacterium which produce spores that are resistant to the environment and can last for years in a hive, said Ernesto Guzman, director of the Honey Bee Research Centre at the University of Guelph.

Worker bees in the hive can transport the spores and spread the disease, Guzman said, but it’s the bees in the larval stage that show clinical symptoms of infection.

“If they ingest enough of those spores, they will typically break down and putrify in the hive,” added Stephen Pernal, national lead for honey bee research with Agriculture and Agri-Food Canada.

“When they do that, the bacteria multiplies and produces billions of more spores. And those spores can in fact infect other developing bees,” said Pernal, who is also the officer-in-charge of the Beaverlodge Research Farm in northern Alberta.

The decomposing larvae turn dark in colour and have a fishy smell, he said.

American foulbrood disease is often treated “very judiciously” with antibiotics in North America, but there are cases where hives containing tens of thousands of bees have to be burned, Pernal said.

Having a vaccine is “another tool in our tool box” to combat the disease, he said.

Protecting honey bees from disease is “extremely important” for human food production, Guzman said.

“It is estimated that one-third of the food that we consume in western societies is produced thanks to the pollination services of bees,” he said.

If the vaccine is effective, it can reduce the use of antibiotics, which “lessens the possibility that (an) antibiotic may be carried over into honey and enter the human food chain,” Pernal added.

“Honey certainly is a product that is tested for various things including antibiotics, but anytime you lessen that input in the system — whether it’s honey bees or the production of other livestock in Canada — that’s a desirable thing,” he said.

The vaccine contains dead Paenibacillus larvae bacteria and works by getting the queen bee, which lays the eggs, to ingest it. The immunity protection from the vaccine is passed along to the developing larval bees.

The vaccine is mixed into a powdered sugar and glucose syrup paste that the worker bees eat and their secretions are fed to the queen bee.

Research trials funded by Dalan Animal Health showed a 30 to 50 per cent decrease in American foulbrood infection among honey bee larvae whose queen bee received the vaccine compared to placebo hives.

The key, both Guzman and Pernal said, will be to see if the vaccine has the same effect in the real world, noting that the trials were conducted in lab-controlled environments.

“If it ends up working when more trials are conducted at the field levels, it will be a great tool to control that particular disease,” Guzman said.

“(It) also may pave the way to develop other vaccines that could be useful in beekeeping and in the insect industry,” he said.

The vaccine is expected to be “distributed on a limited basis to commercial beekeepers in Canada … starting in Spring 2024,” Dalan Animal Health said in a news release.

The Canadian Food Inspection Agency approved the vaccine in late September, a company spokesperson said in an email.

This report by The Canadian Press was first published Oct. 20, 2023.

Canadian Press health coverage receives support through a partnership with the Canadian Medical Association. CP is solely responsible for this content.

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Canada to donate up to 200,000 vaccine doses to combat mpox outbreaks in Africa

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The Canadian government says it will donate up to 200,000 vaccine doses to fight the mpox outbreak in Congo and other African countries.

It says the donated doses of Imvamune will come from Canada’s existing supply and will not affect the country’s preparedness for mpox cases in this country.

Minister of Health Mark Holland says the donation “will help to protect those in the most affected regions of Africa and will help prevent further spread of the virus.”

Dr. Madhukar Pai, Canada research chair in epidemiology and global health, says although the donation is welcome, it is a very small portion of the estimated 10 million vaccine doses needed to control the outbreak.

Vaccine donations from wealthier countries have only recently started arriving in Africa, almost a month after the World Health Organization declared the mpox outbreak a public health emergency of international concern.

A few days after the declaration in August, Global Affairs Canada announced a contribution of $1 million for mpox surveillance, diagnostic tools, research and community awareness in Africa.

On Thursday, the Africa Centres for Disease Control and Prevention said mpox is still on the rise and that testing rates are “insufficient” across the continent.

Jason Kindrachuk, Canada research chair in emerging viruses at the University of Manitoba, said donating vaccines, in addition to supporting surveillance and diagnostic tests, is “massively important.”

But Kindrachuk, who has worked on the ground in Congo during the epidemic, also said that the international response to the mpox outbreak is “better late than never (but) better never late.”

“It would have been fantastic for us globally to not be in this position by having provided doses a much, much longer time prior than when we are,” he said, noting that the outbreak of clade I mpox in Congo started in early 2023.

Clade II mpox, endemic in regions of West Africa, came to the world’s attention even earlier — in 2022 — as that strain of virus spread to other countries, including Canada.

Two doses are recommended for mpox vaccination, so the donation may only benefit 100,000 people, Pai said.

Pai questioned whether Canada is contributing enough, as the federal government hasn’t said what percentage of its mpox vaccine stockpile it is donating.

“Small donations are simply not going to help end this crisis. We need to show greater solidarity and support,” he said in an email.

“That is the biggest lesson from the COVID-19 pandemic — our collective safety is tied with that of other nations.”

This report by The Canadian Press was first published Sept. 13, 2024.

Canadian Press health coverage receives support through a partnership with the Canadian Medical Association. CP is solely responsible for this content.

The Canadian Press. All rights reserved.

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How many Nova Scotians are on the doctor wait-list? Number hit 160,000 in June

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HALIFAX – The Nova Scotia government says it could be months before it reveals how many people are on the wait-list for a family doctor.

The head of the province’s health authority told reporters Wednesday that the government won’t release updated data until the 160,000 people who were on the wait-list in June are contacted to verify whether they still need primary care.

Karen Oldfield said Nova Scotia Health is working on validating the primary care wait-list data before posting new numbers, and that work may take a matter of months. The most recent public wait-list figures are from June 1, when 160,234 people, or about 16 per cent of the population, were on it.

“It’s going to take time to make 160,000 calls,” Oldfield said. “We are not talking weeks, we are talking months.”

The interim CEO and president of Nova Scotia Health said people on the list are being asked where they live, whether they still need a family doctor, and to give an update on their health.

A spokesperson with the province’s Health Department says the government and its health authority are “working hard” to turn the wait-list registry into a useful tool, adding that the data will be shared once it is validated.

Nova Scotia’s NDP are calling on Premier Tim Houston to immediately release statistics on how many people are looking for a family doctor. On Tuesday, the NDP introduced a bill that would require the health minister to make the number public every month.

“It is unacceptable for the list to be more than three months out of date,” NDP Leader Claudia Chender said Tuesday.

Chender said releasing this data regularly is vital so Nova Scotians can track the government’s progress on its main 2021 campaign promise: fixing health care.

The number of people in need of a family doctor has more than doubled between the 2021 summer election campaign and June 2024. Since September 2021 about 300 doctors have been added to the provincial health system, the Health Department said.

“We’ll know if Tim Houston is keeping his 2021 election promise to fix health care when Nova Scotians are attached to primary care,” Chender said.

This report by The Canadian Press was first published Sept. 11, 2024.

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Newfoundland and Labrador monitoring rise in whooping cough cases: medical officer

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ST. JOHN’S, N.L. – Newfoundland and Labrador‘s chief medical officer is monitoring the rise of whooping cough infections across the province as cases of the highly contagious disease continue to grow across Canada.

Dr. Janice Fitzgerald says that so far this year, the province has recorded 230 confirmed cases of the vaccine-preventable respiratory tract infection, also known as pertussis.

Late last month, Quebec reported more than 11,000 cases during the same time period, while Ontario counted 470 cases, well above the five-year average of 98. In Quebec, the majority of patients are between the ages of 10 and 14.

Meanwhile, New Brunswick has declared a whooping cough outbreak across the province. A total of 141 cases were reported by last month, exceeding the five-year average of 34.

The disease can lead to severe complications among vulnerable populations including infants, who are at the highest risk of suffering from complications like pneumonia and seizures. Symptoms may start with a runny nose, mild fever and cough, then progress to severe coughing accompanied by a distinctive “whooping” sound during inhalation.

“The public, especially pregnant people and those in close contact with infants, are encouraged to be aware of symptoms related to pertussis and to ensure vaccinations are up to date,” Newfoundland and Labrador’s Health Department said in a statement.

Whooping cough can be treated with antibiotics, but vaccination is the most effective way to control the spread of the disease. As a result, the province has expanded immunization efforts this school year. While booster doses are already offered in Grade 9, the vaccine is now being offered to Grade 8 students as well.

Public health officials say whooping cough is a cyclical disease that increases every two to five or six years.

Meanwhile, New Brunswick’s acting chief medical officer of health expects the current case count to get worse before tapering off.

A rise in whooping cough cases has also been reported in the United States and elsewhere. The Pan American Health Organization issued an alert in July encouraging countries to ramp up their surveillance and vaccination coverage.

This report by The Canadian Press was first published Sept. 10, 2024.

The Canadian Press. All rights reserved.

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