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World's oldest DNA sequenced from million-year-old mammoths – CTV News

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Teeth from mammoths buried in the Siberian permafrost for more than a million years have yielded the world’s oldest DNA ever sequenced, according to a study published on Wednesday, shining the genetic searchlight into the deep past. 

Researchers said the three specimens, one roughly 800,000 years old and two over a million years old, provide important insights into the giant Ice Age mammals, including the ancient heritage of the woolly mammoth.    

The genomes far exceed the oldest previously sequenced DNA — a horse dating between 780,000 to 560,000 years ago.

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“This DNA is incredibly old. The samples are a thousand times older than Viking remains, and even pre-date the existence of humans and Neanderthals,” said Love Dalen, a professor of evolutionary genetics at the Centre for Palaeogenetics in Stockholm, senior author of the study published in Nature.

The mammoths were originally discovered in the 1970s in Siberia and held at the Russian Academy of Sciences in Moscow. 

Researchers first dated the specimens geologically, with comparisons to other species, like small rodents, known to be unique to particular time periods and found in the same sedimentary layers. 

This suggested that two of the mammals were ancient steppe mammoths more than a million years old.

The youngest of the trio is one of the earliest woolly mammoths yet found.

DNA JIGSAW

They also extracted genetic data from tiny samples of powder from each mammoth tooth, “essentially like a pinch of salt you would put on your dinner plate,” Dalen told a press briefing. 

While it had degraded into very small fragments, scientists were able to sequence tens of millions of chemical base pairs, which make up the strands of DNA, and conduct age estimates from genetic information.

This suggested that the oldest mammoth, named Krestovka, is even older at approximately 1.65 million years old, while the second, Adycha, is around 1.34 million years old, and the youngest Chukochya is 870,000 years old.

Dalen said the discrepancy for the oldest mammoth could be an underestimation in the DNA dating process, meaning the creature was likely around 1.2 million years old, as suggested by the geological evidence. 

But he said it was possible the specimen was indeed older and had thawed out of the permafrost at one point and then become wedged in a younger layer of sediment.

The DNA fragments were like a puzzle with millions of tiny pieces, “way, way, way smaller than you would get from modern high quality DNA”, said lead author Tom van der Valk, of the Science for Life Laboratory, Uppsala University.

Using a genome from an African elephant, a modern relative of the mammoth, as a blueprint for their algorithm, researchers were able to reconstruct parts of the mammoth genomes.

The study found that the older Krestovka mammoth represents a previously unrecognised genetic lineage, which researchers estimated diverged from other mammoths around two million years ago and was ancestral to those that colonised North America.

The study also traced the lineage from the million-year-old Adycha steppe mammoth to Chukochya and other more recent woolly mammoths. 

It found gene variants associated with life in the Arctic, like hairiness, thermoregulation, fat deposits and cold tolerance in the older specimen, suggesting mammoths were already hairy long before the woolly mammoth emerged.

Siberia has alternated between dry and cold Ice Age conditions and warm, wet periods.

Now climate change is melting the permafrost and revealing more specimens, Dalen said, although higher rainfall could mean remains are washed away.

He said new technologies mean it may be possible to sequence even older DNA from remains found in the permafrost, which dates back 2.6 million years.

Researchers are keen to look at creatures such as the ancestors of moose, muskox, wolves, and lemmings, to shine a light on the evolution of modern species. 

“Genomics has been pushed into deep time by the giants of the Ice Age,” said Alfred Roca, a professor in the Department of Animal Sciences at the University of Illinois, in a comment piece published in Nature. 

“The wee mammals that surrounded them might soon also have their day.”

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SpaceX launch marks 300th successful booster landing – Phys.org

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Credit: Unsplash/CC0 Public Domain

SpaceX sent up the 30th launch from the Space Coast for the year on the evening of April 23, a mission that also featured the company’s 300th successful booster recovery.

A Falcon 9 rocket carrying 23 of SpaceX’s Starlink internet satellites blasted off at 6:17 p.m. Eastern time from Cape Canaveral Space Force Station’s Space Launch Complex 40.

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The first-stage booster set a milestone of the 300th time a Falcon 9 or Falcon Heavy booster made a successful recovery landing, and the 270th time SpaceX has reflown a booster.

This particular booster made its ninth trip to space, a resume that includes one human spaceflight, Crew-6. It made its latest recovery landing downrange on the droneship Just Read the Instructions in the Atlantic Ocean.

The company’s first successful booster recovery came in December 2015, and it has not had a failed booster landing since February 2021.

The current record holder for flights flew 11 days ago making its 20th trip off the .

SpaceX has been responsible for all but two of the launches this year from either Kennedy Space Center or Cape Canaveral with United Launch Alliance having launched the other two.

SpaceX could knock out more launches before the end of the month, putting the Space Coast on pace to hit more than 90 by the end of the year, but the rate of launches by SpaceX is also set to pick up for the remainder of the year with some turnaround times at the Cape’s SLC-40 coming in less than three days.

That could amp up frequency so the Space Coast could surpass 100 launches before the end of the year, with the majority coming from SpaceX. It hosted 72 launches in 2023.

More launches from ULA are on tap as well, though, including the May 6 launch atop an Atlas V rocket of the Boeing CST-100 Starliner with a pair of NASA astronauts to the International Space Station.

ULA is also preparing for the second launch ever of its new Vulcan Centaur rocket, which recently received its second Blue Origin BE-4 engine and is just waiting on the payload, Sierra Space’s Dream Chaser spacecraft, to make its way to the Space Coast.

Blue Origin has its own it wants to launch this year as well, with New Glenn making its debut as early as September, according to SLD 45’s range manifest.

2024 Orlando Sentinel. Distributed by Tribune Content Agency, LLC.

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SpaceX launch marks 300th successful booster landing (2024, April 24)
retrieved 24 April 2024
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Wildlife Wednesday: loons are suffering as water clarity diminishes – Canadian Geographic

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The common loon, that icon of northern wilderness, is under threat from climate change due to declining water clarity. Published earlier this month in the journal Ecology, a study conducted by biologists from Chapman University and Rensselaer Polytechnic Institute in the U.S. has demonstrated the first clear evidence of an effect of climate change on this species whose distinct call is so tied to the soundscape of Canada’s lakes and wetlands.

Through the course of their research, the scientists found that July rainfall results in reduced July water clarify in loon territories in Northern Wisconsin. In turn, this makes it difficult for adult loons to find and capture their prey — mainly small fish — underwater, meaning they are unable to meet their chicks’ metabolic needs. Undernourished, the chicks face higher mortality rates. The consistent foraging techniques used by loons across their range means this impact is likely echoed wherever they are found — from Alaska to Canada to Iceland.

The researchers used Landsat imagery to find that there has been a 25-year consistent decline in water clarity, and during this period, body weights of adult loon and chicks alike have also declined. With July being the month of most rapid growth in young loons, the study also pinpointed water clarity in July as being the greatest predictor of loon body weight. 

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One explanation for why heavier rainfall leads to reduced water clarity is the rain might carry dissolved organic matter into lakes from adjacent streams and shoreline areas. Lawn fertilizers, pet waste and septic system leaks may also be to blame.

The researchers, led by Chapman University professor Walter Piper, hope to use these insights to further conservation efforts for this bird Piper describes as both “so beloved and so poorly understood.”

Return of the king

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Giant prehistoric salmon had tusk-like teeth for defence, building nests

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The artwork and publicity materials showcasing a giant salmon that lived five million years ago were ready to go to promote a new exhibit, when the discovery of two fossilized skulls immediately changed what researchers knew about the fish.

Initial fossil discoveries of the 2.7-metre-long salmon in Oregon in the 1970s were incomplete and had led researchers to mistakenly suggest the fish had fang-like teeth.

It was dubbed the “sabre-toothed salmon” and became a kind of mascot for the Museum of Natural and Cultural History at the University of Oregon, says researcher Edward Davis.

But then came discovery of two skulls in 2014.

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Davis, a member of the team that found the skulls, says it wasn’t until they got back to the lab that he realized the significance of the discovery that has led to the renaming of the fish in a new, peer-reviewed study.

“There were these two skulls staring at me with sideways teeth,” says Davis, an associate professor in the department of earth sciences at the university.

In that position, the tusk-like teeth could not have been used for biting, he says.

“That was definitely a surprising moment,” says Davis, who serves as director of the Condon Fossil Collection at the university’s Museum of Natural and Cultural History.

“I realized that all of the artwork and all of the publicity materials and bumper stickers and buttons and T-shirts we had just made two months prior, for the new exhibit, were all out of date,” he says with a laugh.

Davis is co-author of the new study in the journal PLOS One, which renames the giant fish the “spike-toothed salmon.”

It says the salmon used the tusk-like spikes for building nests to spawn, and as defence mechanisms against predators and other salmon.

The salmon lived about five million years ago at a time when Earth was transitioning from warmer to relatively cooler conditions, Davis says.

It’s hard to know exactly why the relatives of today’s sockeye went extinct, but Davis says the cooler conditions would have affected the productivity of the Pacific Ocean and the amount of rain feeding rivers that served as their spawning areas.

Another co-author, Brian Sidlauskas, says a fish the size of the spike-toothed salmon must have been targeted by predators such as killer whales or sharks.

“I like to think … it’s almost like a sledgehammer, these salmon swinging their head back and forth in order to fend off things that might want to feast on them,” he says.

Sidlauskas says analysis by the lead author of the paper, Kerin Claeson, found both male and female salmon had the “multi-functional” spike-tooth feature.

“That’s part of our reason for hypothesizing that this tooth is multi-functional … It could easily be for digging out nests,” he says.

“Think about how big the (nest) would have to be for an animal of this size, and then carving it out in what’s probably pretty shallow water; and so having an extra digging tool attached to your head could be really useful.”

Sidlauskas says the giant salmon help researchers understand the boundaries of what’s possible with the evolution of salmon, but they also capture the human imagination and a sense of wonder about what’s possible on Earth.

“I think it helps us value a little more what we do still have, or I hope that it does. That animal is no longer with us, but it is a product of the same biosphere that sustains us.”

This report by The Canadian Press was first published April 24, 2024.

Brenna Owen, The Canadian Press

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