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Single-shot vaccine's other advantages may soon outweigh lower efficacy, Fauci says – CTV News

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WASHINGTON —
Johnson and Johnson’s forthcoming single-shot COVID-19 vaccine has more going for it than just a middling ability to prevent infection, the pre-eminent U.S. expert on infectious disease said Monday.

Dr. Anthony Fauci, President Joe Biden’s chief medical adviser and the public face of the pandemic battle in the United States, is urging people to look past the shot’s 72 per cent efficacy rate.

The Johnson and Johnson vaccine, expected to be the next one to receive emergency authorization from the U.S. Food and Drug Administration, has proven very effective at preventing death and hospitalization, Fauci said.

It’s also relatively cheap to manufacture. And it doesn’t require deep-freeze transportation and storage or double doses like its Moderna and Pfizer-BioNTech predecessors, both of which boast 95 per cent efficacy but are in short supply.

“There’s a lot more to protection than just preventing (people) from getting infected,” Fauci told an online media briefing.

“We want to keep people out of the hospital, and we don’t want people to die. And in that regard, this will be value-added, not only in the United States, but certainly in the developing world.”

In South Africa, for instance, Fauci said his colleagues are looking forward to getting a vaccine that doesn’t have the logistical challenges of the Pfizer and Moderna offerings.

“You cannot imagine how excited they are,” he said. “The idea of getting a minimal-cold-chain-required, cheap, one-shot vaccine means an awful lot.”

Fauci, CDC director Rochelle Walensky and Andy Slavitt, the senior adviser to the White House COVID-19 response team, have been using their thrice-weekly briefings to educate the world about the many virtues of vaccination in a pandemic.

It’s as much about denying the virus a “playing field” — an unvaccinated host, where it can continue to develop dangerous mutations — as it is about protecting individuals, they point out.

And that requires as many vaccines and vaccinations as possible, as quickly as possible, everywhere around the world, not just in the United States.

“Not only are you going to protect individuals from getting disease, not only are you going to protect them from getting infected, but you are going to prevent the emergence of variants here in our country,” Fauci said.

“The only way we’re going to completely stop mutants is if we stop this throughout the world.”

In an editorial in Sunday’s Wall Street Journal, former FDA commissioner Scott Gottlieb delivered a similar, if simpler, message: the more the merrier.

“Crushing COVID will require making the most of the different vaccine candidates, which come with their own pros and cons, and tweaking them to stay ahead of viral mutations,” Gottlieb wrote.

“New variants of COVID may demand vaccines that offer slightly different layers of protection and target slightly different parts of the virus. The regulatory process must encourage this kind of portfolio diversification, while allowing tweaks to keep ahead of the virus’s twists and turns.”

Dr. Theresa Tam, Canada’s chief public health officer, was asked last week whether different vaccines should be aimed at different demographic groups.

Time will tell, Tam said.

“We will have to look at the data in relation to that particular vaccine: in the clinical trials, what age groups were looked at and other specific information that will help us provide those recommendations,” she said.

Different vaccines have different characteristics, and some may lend themselves to different applications than others, she added.

“Those other kinds of characteristics and criteria — that will be reviewed for (on) who do we best use the supplies that we may get of new vaccines.”

More cases of the COVID-19 variants first identified in the United Kingdom and South Africa are being detected in the U.S. each day, although that could be in part because of improved detection methods, Walensky said.

“CDC has been working on multiple fronts to improve our ability to adapt and understand these variants,” she said.

“The recent rise in the number of variants detected in the United States is likely due at least in part to our expanded ability to sequence their virus samples.”

This report by The Canadian Press was first published Feb. 1, 2021.

With files from Mia Rabson in Ottawa

 

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Roots sees room for expansion in activewear, reports $5.2M Q2 loss and sales drop

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TORONTO – Roots Corp. may have built its brand on all things comfy and cosy, but its CEO says activewear is now “really becoming a core part” of the brand.

The category, which at Roots spans leggings, tracksuits, sports bras and bike shorts, has seen such sustained double-digit growth that Meghan Roach plans to make it a key part of the business’ future.

“It’s an area … you will see us continue to expand upon,” she told analysts on a Friday call.

The Toronto-based retailer’s push into activewear has taken shape over many years and included several turns as the official designer and supplier of Team Canada’s Olympic uniform.

But consumers have had plenty of choice when it comes to workout gear and other apparel suited to their sporting needs. On top of the slew of athletic brands like Nike and Adidas, shoppers have also gravitated toward Lululemon Athletica Inc., Alo and Vuori, ramping up competition in the activewear category.

Roach feels Roots’ toehold in the category stems from the fit, feel and following its merchandise has cultivated.

“Our product really resonates with (shoppers) because you can wear it through multiple different use cases and occasions,” she said.

“We’ve been seeing customers come back again and again for some of these core products in our activewear collection.”

Her remarks came the same day as Roots revealed it lost $5.2 million in its latest quarter compared with a loss of $5.3 million in the same quarter last year.

The company said the second-quarter loss amounted to 13 cents per diluted share for the quarter ended Aug. 3, the same as a year earlier.

In presenting the results, Roach reminded analysts that the first half of the year is usually “seasonally small,” representing just 30 per cent of the company’s annual sales.

Sales for the second quarter totalled $47.7 million, down from $49.4 million in the same quarter last year.

The move lower came as direct-to-consumer sales amounted to $36.4 million, down from $37.1 million a year earlier, as comparable sales edged down 0.2 per cent.

The numbers reflect the fact that Roots continued to grapple with inventory challenges in the company’s Cooper fleece line that first cropped up in its previous quarter.

Roots recently began to use artificial intelligence to assist with daily inventory replenishments and said more tools helping with allocation will go live in the next quarter.

Beyond that time period, the company intends to keep exploring AI and renovate more of its stores.

It will also re-evaluate its design ranks.

Roots announced Friday that chief product officer Karuna Scheinfeld has stepped down.

Rather than fill the role, the company plans to hire senior level design talent with international experience in the outdoor and activewear sectors who will take on tasks previously done by the chief product officer.

This report by The Canadian Press was first published Sept. 13, 2024.

Companies in this story: (TSX:ROOT)

The Canadian Press. All rights reserved.

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Talks on today over HandyDART strike affecting vulnerable people in Metro Vancouver

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VANCOUVER – Mediated talks between the union representing HandyDART workers in Metro Vancouver and its employer, Transdev, are set to resume today as a strike that has stopped most services drags into a second week.

No timeline has been set for the length of the negotiations, but Joe McCann, president of the Amalgamated Transit Union Local 1724, says they are willing to stay there as long as it takes, even if talks drag on all night.

About 600 employees of the door-to-door transit service for people unable to navigate the conventional transit system have been on strike since last Tuesday, pausing service for all but essential medical trips.

Hundreds of drivers rallied outside TransLink’s head office earlier this week, calling for the transportation provider to intervene in the dispute with Transdev, which was contracted to oversee HandyDART service.

Transdev said earlier this week that it will provide a reply to the union’s latest proposal on Thursday.

A statement from the company said it “strongly believes” that their employees deserve fair wages, and that a fair contract “must balance the needs of their employees, clients and taxpayers.”

This report by The Canadian Press was first published Sept. 12, 2024.

The Canadian Press. All rights reserved.

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Transat AT reports $39.9M Q3 loss compared with $57.3M profit a year earlier

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MONTREAL – Travel company Transat AT Inc. reported a loss in its latest quarter compared with a profit a year earlier as its revenue edged lower.

The parent company of Air Transat says it lost $39.9 million or $1.03 per diluted share in its quarter ended July 31.

The result compared with a profit of $57.3 million or $1.49 per diluted share a year earlier.

Revenue in what was the company’s third quarter totalled $736.2 million, down from $746.3 million in the same quarter last year.

On an adjusted basis, Transat says it lost $1.10 per share in its latest quarter compared with an adjusted profit of $1.10 per share a year earlier.

Transat chief executive Annick Guérard says demand for leisure travel remains healthy, as evidenced by higher traffic, but consumers are increasingly price conscious given the current economic uncertainty.

This report by The Canadian Press was first published Sept. 12, 2024.

Companies in this story: (TSX:TRZ)

The Canadian Press. All rights reserved.

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