Health
Here's What to Know About Pfizer's 'Extra' COVID Vaccine Doses – Motley Fool
Pfizer (NYSE:PFE) began shipping its COVID-19 vaccine for U.S. use nearly two weeks ago. The label on each vial of BNT162b2 states that there are five doses included. However, some pharmacists discovered that some vials actually have more than five doses. In this Motley Fool Live video recorded on Dec. 18, 2020, healthcare and cannabis bureau editor/analyst Olivia Zitkus and Fool.com writer Keith Speights talk about what’s the story behind these “extra” doses of Pfizer’s COVID-19 vaccine.
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Olivia Zitkus: Let’s turn to Pfizer. A lot’s happened after the vaccine started its rollout in the U.S. this week. A couple of interesting problems have come to light, and I want to touch on two of them.
You both had a really important one talking about the allergic reaction and all the attention they’ve gotten from Alaska. Number one, apparently, there might be more doses per vial than originally thought in some of the Pfizer vials that have already been distributed. What does this mean? Is it a happy accident for the hospitals and pharmacies that come across this, or is it a red flag that the company just doesn’t know how many doses of the vaccine it’s actually distributing?
Keith Speights: [laughs] I think it’s happy, but not necessarily an accident, Olivia. It’s not uncommon for drug makers to overfill the vials just a little. I think that’s exactly what we’re seeing here, is that there’s some overfilling.
In some cases, pharmacists have discovered that they could get six or seven doses out of a vial that the label says that it only has five doses. Actually, there was even some confusion initially where some pharmacists were throwing away the extra doses they were able to obtain. That’s not great, and so the FDA had to come out and say, “No, you can use these doses.”
So it’s not an accident because, again, drugmakers do intentionally overfill in some cases. There are some reasons for that. Syringes used in different settings sometimes have small effects on the size of the dose. That’s one reason for the slight overfilling.
There could even be changes in air pressure at different locations and different altitudes that affect the volume of the vaccine in a vial. There are reasons behind a little bit of overfilling there.
The good news, the happy part of this is that the number of doses that we could have from Pfizer’s vaccine is going to be higher than some of the predictions as a result of this. How much? We don’t know, but it’s certainly good news.
Olivia Zitkus: Sure. So there could be a lot of different explanations for overfill, not all bad.
Metro Manila (CNN Philippines, January 15) — US drugmaker Pfizer is aiming to provide developing countries like the Philippines doses of its COVID-19 vaccine at an affordable price.
“I’m also very happy to announce that it is Pfizer’s intention to make available its COVID-19 vaccine to low-income countries like the Philippines at a not-for-profit price during the pandemic,” said Andreas Quercia, Pfizer country manager during the Senate Committee on the Whole’s hearing on the national COVID-19 vaccination plan Friday.
Pfizer also said it is in “advance discussions” with the Philippine government on a supply agreement for its COVID-19 vaccine, adding it plans to make doses available to the country as soon as possible. Vaccine czar Carlito Galvez Jr., meanwhile, said there might already be a term sheet and supply agreement with the pharmaceutical firm within next week.
The official also said Pfizer vaccine doses may reach the Philippines as early as the first quarter of 2021 through the help of the COVAX facility, of which the country is part of. The facility purchases vaccines to be distributed for free to developing countries, covering a maximum of 20% of their respective populations.
Pfizer is the first to secure Emergency Use Authorization in the Philippines for a coronavirus vaccine. The Food and Drug Administration granted the approval Thursday, citing the vaccine’s high efficacy rate.
Pfizer earlier bagged EUAs across the globe, including from the United States and the United Kingdom.
Agreements with Sinovac, other firms not a ‘done deal’
When asked whether agreements the country has entered into in advance for vaccine supply with firms like China-based Sinovac are already a “done deal,” Galvez said that is not the case.
“Ang sa atin pa lang po ngayon [For now,] we are [just] dealing with the term sheet. Posible rin [It could also be possible] we have to lock (the supply), so that they can already make production. So sa ngayon po, wala pa pong government funds tayong naibibigay,” clarified the official.
[Translation: As of now, we haven’t given out government funds yet.]
National policy against COVID-19 deputy chief implementer Vince Dizon also reiterated the country’s vaccine expert panel has recommended seven vaccine brands for possible purchase, which includes Sinovac. However, none of this is final yet, as the government awaits the panel’s final recommendation, along with an EUA from the FDA.
Sinovac has also applied for emergency use authorization, the regulatory agency revealed earlier this week.
The rapid expansion of COVID-19 vaccinations to senior citizens across the U.S. has led to bottlenecks, system crashes and hard feelings in many states because of overwhelming demand for the shots.
Mississippi’s Health Department stopped taking new appointments the same day it began accepting them because of a “monumental surge” in requests. People had to wait hours to book vaccinations through a state website or a toll-free number Tuesday and Wednesday, and many were booted off the site because of technical problems and had to start over.
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In California, counties begged for more coronavirus vaccine to reach millions of their senior citizens. Hospitals in South Carolina ran out of appointment slots within hours. Phone lines were jammed in Georgia.
“It’s chaos,” said New York City resident Joan Jeffri, 76, who had to deal with broken hospital web links and unanswered phone calls before her daughter helped her secure an appointment. “If they want to vaccinate 80% of the population, good luck, if this is the system. We’ll be here in five years.”
Up until the past few days, health care workers and nursing home patients had been given priority in most places around the U.S. But amid frustration over the slow rollout, states have thrown open the line to many of the nation’s 54 million senior citizens with the blessing of President Donald Trump’s administration, though the minimum age varies from place to place, at 65, 70 or higher.
On Thursday, New Jersey expanded vaccinations to people between 16 and 65 with certain medical conditions — including up to 2 million smokers, who are more prone to health complications.
The U.S., meanwhile, recorded 3,848 deaths on Wednesday, down from an all-time high of 4,327 the day before, according to Johns Hopkins University. The nation’s overall death toll from COVID-19 has topped 385,000.
President-elect Joe Biden unveiled a $1.9 trillion coronavirus plan Thursday that includes speeding up vaccinations. Called the “American Rescue Plan,” the legislative proposal would meet Biden’s goal of administering 100 million vaccines by the 100th day of his administration.
More than 11.1 million Americans, or over 3% of the U.S. population, have gotten their first shot of the vaccine, a gain of about 800,000 from the day before, the Centers for Disease Control and Prevention said Thursday. The goal of inoculating anywhere between 70% and 85% of the population to achieve herd immunity and conquer the outbreak is still many months away.
Hard-hit Los Angeles County, the nation’s most populous county with 10 million residents, said it couldn’t immediately provide shots to the elderly because it had inoculated only about a quarter of its 800,000 health care workers.
“We’re not done with our health care workers, and we actually don’t have enough vaccine right now to be able to get done more quickly,” Public Health Director Barbara Ferrer said. “We haven’t heard back from the state about vaccine availability and how it would be distributed.”
Santa Clara County health officials said the county of 2 million people had only enough vaccine to inoculate people 75 and older, not the 65-and-older crowd.
“It’s almost like a beauty contest. And this should not be a beauty contest,” County Supervisor Cindy Chavez said. “This is about life and death.”
In Mississippi, officials said new appointments will probably have to wait until a hoped-for shipment of vaccine in mid-February.
In South Carolina, Kershaw Health in Camden implored people not to call its hospitals or doctors to schedule vaccination appointments after receiving more than 1,000 requests in two days. State health authorities said their hot line got 5,000 calls on Wednesday.
Francis Clark said she tried repeatedly to schedule an appointment for her 81-year-old mother, who lives alone outside Florence, South Carolina, and doesn’t have internet access. But the local hospital had no openings on Wednesday, Clark said, and the other vaccination sites are too far away.
“My mom can’t drive to Charleston,” Clark said. “She’s too old.”
Allison Salerno, an audio producer from Athens, Georgia, said she spent the better part of a day calling her state’s health department to get a vaccine appointment for her 89-year-old mother.
“I started calling at 8:30 a.m. and on the 67th call I was finally put on hold,” Salerno said. “I had already pre-registered her two weeks before online, but I never received a confirmation.”
After Salerno had spent 65 minutes on hold, someone finally came on the line and gave her mother a Saturday appointment.
“My mother has not been out since the beginning of the pandemic,” Salerno said. “She’s a very healthy woman and she wants to go to the grocery store, she wants to get her hair done.”
Meanwhile, some states, like Minnesota, are waiting before throwing open the doors.
“As we learn more, we will work to make sure everyone who is eligible for a vaccine knows how, where, and when they can get their shots,” the state Health Department said in an email. “Everyone’s opportunity to get vaccinated will come; it will just take some time.”
Arizona, which had the nation’s highest COVID-19 diagnosis rate over the past week, will start signing up people 65 and older next week. It also plans to open a vaccination site at Phoenix Municipal Stadium in addition to the one dispensing thousands of shots daily at the home of the NFL’s Arizona Cardinals.
To step up the pace of vaccinations, South Carolina made a rule change allowing medical students, retired nurses and other certain professionals to administer the shots.
California lawmakers are increasing the pressure on Gov. Gavin Newsom to likewise expand authorization for who can give injections to include nursing students, retired medical workers, firefighters and National Guard members with medical training.
Newsom said the state’s priority is to deliver vaccines “as quickly as possible to those who face the gravest consequences.” He urged patience for those not yet eligible, saying: “Your turn is coming.”
Jeffri, the New Yorker, spent several days trying to book a vaccination and once actually received a slot, only to get a follow-up text saying they didn’t have the doses. Finally, with some online sleuthing from her daughter, the retired arts-administration professor got an appointment for her first shot — two weeks from now.
“It’s a relief,” said Jeffri, who wrote to Gov. Andrew Cuomo about her ordeal. “But I’m not sure I trust it until it’s done.”
The rapid expansion of COVID-19 vaccinations to senior citizens across the U.S. has led to bottlenecks, system crashes and hard feelings in many states because of overwhelming demand for the shots.
Mississippi’s Health Department stopped taking new appointments the same day it began accepting them because of a “monumental surge” in requests. People had to wait hours to book vaccinations through a state website or a toll-free number Tuesday and Wednesday, and many were booted off the site because of technical problems and had to start over.
In California, counties begged for more coronavirus vaccines to reach millions of their senior citizens. Hospitals in South Carolina ran out of appointment slots within hours. Phone lines were jammed in Georgia.
“It’s chaos,” said New York City resident Joan Jeffri, 76, who had to deal with broken hospital web links and unanswered phone calls before her daughter helped her secure an appointment. “If they want to vaccinate 80 per cent of the population, good luck, if this is the system. We’ll be here in five years.”
Up until the past few days, health care workers and nursing home patients had been given priority in most places around the U.S. But amid frustration over the slow rollout, states have thrown open the line to many of the nation’s 54 million senior citizens with the blessing of U.S. President Donald Trump’s administration, though the minimum age varies from place to place, at 65, 70 or higher.
On Thursday, New Jersey expanded vaccinations to people between 16 and 65 with certain medical conditions — including up to two million smokers, who are more prone to health complications.
The U.S., meanwhile, recorded 3,848 deaths on Wednesday, down from an all-time high of 4,327 the day before, according to Johns Hopkins University. The nation’s overall death toll from COVID-19 has topped 385,000.
President-elect Joe Biden unveiled a $1.9 trillion coronavirus plan Thursday that includes speeding up vaccinations. Called the “American Rescue Plan,” the legislative proposal would meet Biden’s goal of administering 100 million vaccines by the 100th day of his administration.
More than 11.1 million Americans, or over three per cent of the U.S. population, have gotten their first shot of the vaccine, a gain of about 800,000 from the day before, the Centers for Disease Control and Prevention said Thursday. The goal of inoculating anywhere between 70 per cent and 85 per cent of the population to achieve herd immunity and conquer the outbreak is still many months away.
Hard-hit Los Angeles County, the nation’s most populous county with 10 million residents, said it couldn’t immediately provide shots to the elderly because it had inoculated only about a quarter of its 800,000 health care workers.
“We’re not done with our health care workers, and we actually don’t have enough vaccine right now to be able to get done more quickly,” Public Health Director Barbara Ferrer said. “We haven’t heard back from the state about vaccine availability and how it would be distributed.”
Santa Clara County health officials said the county of two million people had only enough vaccine to inoculate people 75 and older, not the 65-and-older crowd.
“It’s almost like a beauty contest. And this should not be a beauty contest,” County Supervisor Cindy Chavez said. “This is about life and death.”
In Mississippi, officials said new appointments will probably have to wait until a hoped-for shipment of vaccine in mid-February.
In South Carolina, Kershaw Health in Camden implored people not to call its hospitals or doctors to schedule vaccination appointments after receiving more than 1,000 requests in two days. State health authorities said their hot line got 5,000 calls on Wednesday.
Francis Clark said she tried repeatedly to schedule an appointment for her 81-year-old mother, who lives alone outside Florence, South Carolina, and doesn’t have internet access. But the local hospital had no openings on Wednesday, Clark said, and the other vaccination sites are too far away.
“My mom can’t drive to Charleston,” Clark said. “She’s too old.”
Allison Salerno, an audio producer from Athens, Georgia, said she spent the better part of a day calling her state’s health department to get a vaccine appointment for her 89-year-old mother.
“I started calling at 8:30 a.m. and on the 67th call I was finally put on hold,” Salerno said. “I had already pre-registered her two weeks before online, but I never received a confirmation.”
After Salerno had spent 65 minutes on hold, someone finally came on the line and gave her mother a Saturday appointment.
“My mother has not been out since the beginning of the pandemic,” Salerno said. “She’s a very healthy woman and she wants to go to the grocery store, she wants to get her hair done.”
Meanwhile, some states, like Minnesota, are waiting before throwing open the doors.
“As we learn more, we will work to make sure everyone who is eligible for a vaccine knows how, where, and when they can get their shots,” the state Health Department said in an email. “Everyone’s opportunity to get vaccinated will come; it will just take some time.”
Arizona, which had the nation’s highest COVID-19 diagnosis rate over the past week, will start signing up people 65 and older next week. It also plans to open a vaccination site at Phoenix Municipal Stadium in addition to the one dispensing thousands of shots daily at the home of the NFL’s Arizona Cardinals.
To step up the pace of vaccinations, South Carolina made a rule change allowing medical students, retired nurses and other certain professionals to administer the shots.
California lawmakers are increasing the pressure on Gov. Gavin Newsom to likewise expand authorization for who can give injections to include nursing students, retired medical workers, firefighters and National Guard members with medical training.
Newsom said the state’s priority is to deliver vaccines “as quickly as possible to those who face the gravest consequences.” He urged patience for those not yet eligible, saying: “Your turn is coming.”
Jeffri, the New Yorker, spent several days trying to book a vaccination and once actually received a slot, only to get a follow-up text saying they didn’t have the doses. Finally, with some online sleuthing from her daughter, the retired arts-administration professor got an appointment for her first shot — two weeks from now.
“It’s a relief,” said Jeffri, who wrote to Gov. Andrew Cuomo about her ordeal. “But I’m not sure I trust it until it’s done.”
© 2021 The Canadian Press
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