Cochrane District EMS testing new opioid drug treatment program
“You overdosed and you were given narcan.”
That’s what Cochrane District EMS operations commander Derrick Cremin told a homeless man, after he had been revived from an opioid overdose.
Paramedics found the man unresponsive outside a local church last week, later learning that he uses fentanyl.
Cremin then went through a checklist of withdrawal symptoms to determine whether the man was eligible for an opioid drug therapy that could save his life.
“We can give you something called Suboxone,” Cremin told the patient.
He then gave him two film tabs of buprenorphine-naloxone, known by the brand name Suboxone.
Without it, the patient may not have survived the week, according to Seamus Murphy, deputy chief of standards and community services.
‘We want to keep people safe’
While lifesaving treatments like naloxone can revive someone from an overdose, Murphy said it also brings on severe withdrawal.
Patients then turn straight to opioids for relief. The condition causes a need to consume more or risk death from withdrawal — as long as the opioid doesn’t kill the user first.
Suboxone can quell those urges by delivering enough opioids to satiate the craving without causing euphoria, along with offering about 24 hours of protection from another overdose.
“We want to keep people safe and that’s what this does,” said Murphy.
“It’s an opioid agonist therapy that treats people that suffer with opiate use.”
Patients then have a clearer mind to make a better choice, he said, ideally choosing to enter into addiction treatment.
First to administer it in Canada
Suboxone is classified as a narcotic and Cochrane District is the first paramedic service in Canada to carry it and administer it in the field.
Only a select few staff are currently allowed to handle it —Cremin is one of them — but all of the service’s paramedics are trained on its use.
Ontario’s Ministry of Health gave the service the green light earlier this month to test the treatment method, with the goal of revolutionizing how EMS respond to overdoses.
Cremin said it’s a reassuring tool to have.
“Before, we would treat these patients, offer them (naloxone) … and they would refuse treatment or transport to the hospital,” he said.
“We really didn’t know what happened to them after the overdose. Now, we know that they’re being transported and they’re going to withdrawal management and, hopefully, seeking the help.”
Having administered Suboxone to at least eight patients, with several agreeing to further treatment at the Timmins and District Hospital’s addiction services department, the hospital’s addictions and mental health program manager, Pat Nowak, said he sees major potential.
Chance to turn a life around
It’s a welcome addition in battling the opioid crisis, he said, as staff struggle to curb opioid fatalities in a city that still holds some of the highest numbers in Ontario.
“EMS might be one of the people that come into contact with people who use substances the most,” Nowak said.
“I think providing that extra avenue to get into treatment, into recovery, is a great idea.”
Suboxone may not be a miracle drug that can single-handedly end the opioid crisis, but Nowak said it can certainly offer a gateway to sobriety and a better life for opioid users who truly want to change their lives.
“Someone overdoses and they’re saying, ‘that’s it, no more’ this is the chance to say, ‘it’s right here, right now,’” he said.
Murphy said he has been presenting his research on Suboxone to paramedic services across the country and that at least 10 are interested in adopting the program.
First, his goal is for every ambulance in his service — and then in the province — to be able to carry the drug and for every paramedic to be able to administer it.
Murphy said it’s an essential tool every paramedic should be able to offer to an overdose victim, as they may not get another chance.
“A life we save today could be a life changed tomorrow and that’s what people have to realize.”
Flavanols are linked to better memory and heart health – here’s what foods you can eat to get these benefits – Yahoo Canada Sports
There are plenty of good reasons to make sure you’re eating enough fruit and vegetables each day. Not only do fruit and vegetables contain many of the important vitamins and minerals our body needs to function at its best, they also keep our gut healthy and may even help maintain a healthy weight.
But some plant foods may be more beneficial for health than others, thanks to a group of compounds called flavanols.
For instance, a recent study I helped conduct showed that people who eat a diet high in flavanol-rich foods may have better memory compared to those who have a low intake. A previous study also found that people with a low intake of flavanols were at higher risk of heart disease. Overall, there’s convincing evidence that consuming enough flavanols has health benefits.
But while research shows that flavanols have many health benefits, it’s important for consumers to know that not all flavanol-rich foods contain the same amount of flavanols – meaning some may be more beneficial to health than others.
Flavanols are a group of compounds that are found in many plants – including apples, berries, plums and even beverages such as tea.
There are two main groups of flavanols, with many different subgroups. Each plant will contain different combinations of flavanols, as well. These compounds each have different structures and different effects on the body. That means that not all flavanols are created equal.
For example, a portion of blueberries and a cup of tea may contain the same amount of total flavanols – but they are made up of completely different types of flavanols, which may have completely different health effects.
So in order to investigate the health effects of flavanols, it’s therefore important to use a source which includes a wide range of different types. This is why flavanols extracted from cocoa are an ideal model, as they contain the two main types of flavanols. It also allows researchers to calculate which other foods are likely to have benefits based on how similar the compounds they contain are to cocoa flavanols.
Since foods such as cocoa, berries and tea contain a combination of many types of flavanols, it’s currently not clear which individual compounds generate health benefits. But some research has linked the specific flavanol epicatechin with better vascular function. Cocoa and tea both contain epicatechin.
Many different types
Another thing to know is that even if a food contains flavanols, it may contain lower amounts compared to others.
To better understand how flavanol intake affects health, a few years ago we developed a test that uses urine to measure flavanol intake. The test is based on the way the human body processes flavanols and tells us whether someone has eaten large amounts, small amounts or no flavanols at all.
Using this test, we were able to show that people with high flavanol intake had lower blood pressure and better memory than those with lower intake.
When we developed the urine test, we also investigated how it is affected by different types of flavanols and foods. This allowed us to estimate what amount of different flavanol-rich foods a person needs to consume to achieve approximately 500mg of flavanols per day – similar to the amount used in studies, which has been shown to have clinical benefit.
According to our research, only two-and-a-half cups of green tea are needed daily to get the recommended 500mg of flavanols. Just under a cup of millet (sorghum grain) can also provide you with the recommended daily amount.
But if you were to try and get your flavanols from one type of fruit and vegetable, our research shows you’d need to consume large amounts of each to achieve the recommended amount. For example, you’d need to consume nearly 15 cups of raspberries alone to get 500mg of flavanols.
As such, the best way to get enough flavanols daily is by consuming a combination of different fruits and vegetables. For example two apples, a portion of pecan nuts and a large portion of strawberries can achieve the 500mg target – or a salad made with millet and fava beans.
It’s also important to note that while the flavanols used in many studies were extracted from cocoa, unfortunately chocolate (even dark chocolate) is a very poor source of flavanols – despite what some headlines might claim. This is because these flavanols are lost during processing.
Although there’s still much we don’t know about flavanols – such as why they have the effect they do on so many aspects of our health – it’s clear from the research we do have that they are very likely beneficial to both memory and heart health.
This article is republished from The Conversation under a Creative Commons license. Read the original article.
Gunter Kuhnle has received research funding from Mars, Inc., a company engaged in flavanol research and flavanol-related commercial activities.
‘Social deprivation’ speeds up aging, and death: McMaster study
We are dying every day, wrote Seneca, a stoic philosopher in ancient Rome.
And if you struggle living alone or have weak familial bonds, you risk speeding up death by as much as one year, according to findings published by McMaster University on Monday.
The new study shows that biological clocks tick faster for those dwelling in an environment of social deprivation (a dearth of family or community network resources) or material poverty, such as lacking access to quality housing, healthy food and recreation.
McMaster’s Divya Joshi, the study’s first author, said the findings indicate that living in a “deprived urban neighbourhood” marked by either form of deprivation is associated with “premature biological aging.”
Joshi is a research associate in the university’s Department of Health Research Methods, Evidence and Impact.
“If your (biological) systems are aging faster than your chronological age, then you will have more poor health outcomes, or quicker health outcomes, than someone who is aging slower biologically,” she told The Spectator.
The study analyzed DNA from the blood samples of 1,445 participants across Canada, who are part of the Canadian Longitudinal Study on Aging that is following 50,000 people between age 45 to 85.
“Epigenetic clocks” studied in the samples — also called “DNA methylation-based estimators” — indicated aging at the cellular level, she said.
“To be able to see that living in a socially or materially deprived neighbourhood impacts your healthy aging; that it increases your risk of epigenetic age acceleration by almost a year, beyond your individual health status — I think that is just remarkable,” she said.
When your biological age outpaces your calendar age, she said you have a greater risk of cardiovascular disease, respiratory conditions and neurological disorders that present a “greater risk of premature mortality.”
The findings fit their research hypothesis, she said, but what didn’t fit was the assumption that depression in the test subjects would further “amplify” the rapid aging effect.
In fact, while depression symptoms also contributed to epigenetic aging, environmental factors impacted aging acceleration regardless of depression symptoms.
The findings were published June 5 in “The Journals of Gerontology, Series A: Biological Sciences and Medical Sciences.”
McMaster professor Parminder Raina led the research team, which included investigators from the Netherlands, Norway and Switzerland, according to a news release.
While the presentation of the findings focused on the connection to disadvantaged neighbourhoods, Joshi agreed that an individual will age more rapidly when deprived of familial or social bonds, regardless of where they live.
“That is true, there is evidence that those people who have poor social networks or broken family units have a greater risk of higher epigenetic age acceleration … It is aging you, and that is so relevant coming out of the pandemic, and the isolation many people experienced, especially the toll it had on our older populations.”
Sudbury health unit offers advice about West Nile Virus – Sudbury.com
The Sudbury health unit is warning area residents to be wary of the possibility of being infected with West Nile Virus.
“Whether you are spending time in your backyard, exploring local trails, or vacationing in Ontario, getting bitten by mosquitos puts you at risk of being infected with West Nile virus,” said the release from Public Health Sudbury and Districts.
The release also said the risk is low, but it is still possible.
“Although the overall risk of becoming infected with West Nile virus is low, everyone is at risk and preventing bites is important to protect yourself and your family,” said Ashley DeRocchis, an environmental support officer with Public Health Sudbury & Districts.
Citizens are advised to use an insect repellent approved by Health Canada and follow the application recommendations on the package.
Also, during the times of day when mosquitoes are most active — during dusk and dawn — people might choose to stay indoors if possible.
The health unit also advised that people can wear light-coloured clothing, including long sleeves, long pants, socks, and a hat whenever they are outdoors. Consider the use of mesh “bug jackets” or “bug hats,” the news release said.
At home, people can check their window and door screens to ensure that there are no tears or holes for mosquitoes to get through. Also, don’t give the bugs a place to lay eggs.
Mosquitoes need only a small amount of calm, standing water to lay their eggs and for larvae to hatch, said PHSD.
Reduce mosquito breeding areas by changing or removing standing water at least once a week from areas such as bird baths. old tires, containers, barrels, flower pot saucers, swimming pool covers, wading pools, clogged gutters and eavestroughs, clogged drainage ditches, small containers like cans or bottle tops and unused children’s toys, said the release.
The health unit said symptoms of West Nile virus can range from mild to severe, from flu-like symptoms to severe nausea and even loss of consciousness.
Public Health Sudbury & Districts will be trapping and testing mosquitoes again this year starting in mid-June and continuing into the fall of 2023, said the release. For more information on West Nile virus, visit the website at phsd.ca or call Public Health Sudbury & Districts at 705-522-9200, ext. 464 (toll-free 1-866-522-9200).
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