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Vaccine limbo: She got one dose of AstraZeneca, and doesn't know what comes next – CTV News

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TORONTO —
One young woman who received the AstraZeneca COVID-19 vaccine is stuck in limbo, waiting to find out what will happen with her second dose, now that health authorities have pressed pause on administering that vaccine to those under age 55.

The 21-year-old Toronto-area resident received her first dose of AstraZeneca from a pharmacy. She said she was able to get the vaccine because the pharmacy had extras.

“I was told by this very government that it was safe, effective, and to take the first vaccine I could get,” Emma Hoffer-Weinper told CTVNews.ca in an email on Wednesday.

She received her first dose on March 17. Less than two weeks later, the National Advisory Committee on Immunization recommended immediately halting use of the AstraZeneca vaccine in people under age 55.

Most provinces were rolling out the AstraZeneca vaccine in older populations, so the number of people under 55 who received a dose of the vaccine is believed to be low.

“There is no information on what to do for us under 55 who have received this vaccine. The number who received it is small, insignificant to many. But we exist,” Hoffer-Weinper added.

She said she feels misled, having initially been told that the vaccine was safe, and the push for everyone to take the first one available to them.

“Be transparent or don’t offer vaccines. We didn’t sign up for a vaccine to be a trial study, we signed up for one that is safe and effective,” she said.

As for next steps, nothing is yet set in stone, but there are two options being considered.

According to Dr. Caroline Quach, chair of NACI, either the AstraZeneca vaccinations will resume in that age group or they will be paused permanently.

“If that is the case, the [second] dose is not due before at least 12 weeks (on label for AZ) and we will have, by then, results from the mixed schedule study that is currently done in the UK where participants are receiving AZ followed by the Pfizer vaccine. This study started recruitment on February 1st,” she told CTVNews.ca in an email on Thursday.

She said at this time, the pause is temporary while Health Canada conducts its enquiry. That doesn’t give people like Hoffer-Weinper a definitive answer. She’ll have to wait to see if Health Canada resumes vaccinations in her age group or pauses indefinitely– and if it’s the latter, what happens next will depend on the British study’s outcome.

While Hoffer-Weinper said she’s had no adverse reactions, she regrets having gotten the AstraZeneca vaccine because of the toll it’s taken on her anxiety.

“It’s in the back of my head every single day that I read the word ‘Pfizer’ or ‘vaccine,’” she told CTVNews.ca in a phone interview on Thursday.

She worries that the confusion over the AstraZeneca vaccine will cause further vaccine hesitancy, especially given the difficulty she had in finding an answer.

“Not everyone wants to research and not everyone knows how to research,” she said. “I spent four years in university and I can’t find information on this, but I can’t even begin to imagine the fear and hesitancy that people will get if they don’t want to, or know how to do that.”

Knowing that she’ll have an answer sooner rather than later has given her some relief, but she wishes she had been told sooner, especially since there seem to be so few people under age 55 who got a dose of AstraZeneca.

“They could have just called us and said ‘don’t worry we’re working on it’, any kind of reassurance, even if they don’t have all the answers,” she said. “Communication is key, I think more so than the actual concrete answers.”

Despite all of the stress and anxiety, she says she hasn’t lost faith in vaccines.

“I think that the vaccines are one of the greatest scientific gifts that we’ll have in our generation,”she said.

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As COVID-19 vaccines for kids get closer, experts weigh up how to reassure parents – CBC.ca

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As Pfizer Inc. and BioNTech say they’ve moved a step closer to providing their COVID-19 vaccine for younger children, one mother says she’s keen to have her eldest vaccinated, but hears some hesitation among other parents.

“As parents, you’re nervous and you’re apprehensive, obviously, about any risks,” said Fallon Jones, who lives in Halifax with a five-year-old daughter and two-year-old son.

“But we have to weigh the pros and the cons here, and I think that this is a good opportunity to protect them against a potentially deadly virus,” she told The Current’s Matt Galloway.

Pfizer-BioNTech said Monday that a clinical trial of its COVID-19 vaccine recorded a robust immune response in five- to 11-year-olds, and the company plans to seek regulatory approval as soon as possible. Children received two shots, each one-third the dose size given to adults. The findings have not been peer-reviewed, nor published.

Pfizer-BioNTech COVID-19 vaccine appears safe, effective in younger kids, expert says

3 days ago

Although he cautions Pfizer-BioNTech has yet to release the raw data supporting the claim that its COVID-19 vaccine is safe and effective in kids aged 5-11, it’s ‘reasonable’ to assume that’s accurate, says Dr. Christopher Labos, a cardiologist with a degree in epidemiology. 2:35

For any vaccine to be approved by Health Canada, the manufacturers supply the necessary clinical trial data for review. If the regulator grants approval, the National Advisory Committee on Immunization (NACI) will make a recommendation on their use, but the final decision to deploy the vaccines rests with provincial authorities.

In a statement to The Current, Health Canada said the makers of all COVID-19 vaccines approved in Canada are conducting or planning studies in adolescents and younger children, but it has so far not received any submission for the approval of any COVID-19 vaccine for children under 12.

In her work at a vaccine hesitancy clinic in Calgary, Dr. Cora Constantinescu meets parents who are experiencing “a lot of fear and anxiety” around their children potentially getting the vaccine.

“We often have parents who are fully vaccinated themselves, who may be hesitant about their kids,” said Constantinescu, a pediatrician and infectious disease doctor at Alberta Children’s Hospital.

She said that parents talk to her about things they’ve seen online, including “anti-vaccine rhetoric and a lot of misconstrued science.”

In Halifax, Jones said she often hears other parents say they don’t know what’s in the vaccine, so they won’t give it to their kids. When she asks if they knew what was in the vaccines their kids received as babies, the response is usually no, she said.

“I completely respect and understand how there would be some fear associated with it,” she said. 

But ultimately, “we trusted our doctors then and we trusted the science then, and we need to do the same with this vaccine.” 

Dr. Cora Constantinescu said that as parents approach the decision, they should consider the negative impacts of COVID-19 on children. (Submitted by Dr. Cora Constantinescu)

How should parents approach vaccine question?

Constantinescu said many parents have seen misinformation on social media, where there is a “huge polarization of the pro-vaccine and the anti-vaccine crowd.”

“The parents are caught in the middle, scared and worried about their kids, trying to make the best decision they can,” she said.

As parents approach the decision, they should consider the dual impact of COVID-19 on children, she said.

“We’re seeing the direct effects of COVID on children, and we know that that can range from mild disease, to respiratory illness, to being hospitalized, having a multi-system inflammation, to ending up in ICU,” she said.

There is also an indirect cost, including mental health issues and issues around socialization, she said.

How a doctor discusses vaccine hesitancy with patients

10 months ago

Dr. Cora Constantinescu, an infectious disease specialist from the Vaccine Hesitancy Clinic in Calgary, discusses how she approaches conversations around vaccine hesitancy, the impact of those conversations and what’s needed in messaging around the COVID-19 vaccine. 3:44

The news from Pfizer-BioNTech gives her hope that those impacts can soon be addressed, but she warned that the data has not yet been made public, or reviewed by Health Canada.

If it is approved, she said parents should approach the vaccine as an issue of “personal protection first.”

“It’s about protecting their kids directly, looking out for them, and wanting to return them to a normal life,” she said.

‘Pull out all the stops’ to protect kids

Dr. Kashif Pirzada, an emergency physician in Toronto, wants to see a safe vaccine for kids approved and available as quickly as possible.

“I’m calling for all of these processes to be speeded up and done very transparently,” said Pirzada, who is also a co-founder of Masks4Canada, a group that advocates for public health measures to slow the spread of the virus.

Dr. Kashif Pirzada said that when a vaccine is approved for younger children, ‘we should pull out all the stops and get these shots into little arms as quickly as possible.’ (Dr. Kashif Pirzada)

He added that more work should be done to reassure parents that the vaccines are safe. He warned that COVID-19 is not harmless to children, and the longer they remain unprotected, the more infections there will be.

In the meantime, vaccination sites and health-care workers could be prepared to ramp the vaccination campaign back up, he said.

“Once that approval comes, we should pull out all the stops and get these shots into little arms as quickly as possible.”


Written by Padraig Moran. Produced by Rachel Levy-McLaughlin, Arianne Robinson and Joana Draghici.

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Gold price drops as Powell talks 'gradual' tapering, downplays Evergrande contagion concerns – Kitco NEWS

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(Kitco News) The gold market saw its earlier gains reversed as Federal Reserve Chair Jerome Powell talked about “gradual” tapering while downplaying China’s Evergrande contagion effect on the U.S. market.

On Wednesday, the Fed said it may soon start tapering its $120 billion in monthly asset purchases, with central bank officials showing growing support for raising interest rates in 2022. 

“If progress continues broadly as expected, the Committee judges that a moderation in the pace of asset purchases may soon be warranted. These asset purchases help foster smooth market functioning and accommodative financial conditions, thereby supporting the flow of credit to households and businesses,” the Fed said in a statement.

When clarifying the Fed’s stance at a press conference following the Fed statement, Powell indicated that it would be a “very gradual taper,” which could conclude in the middle of next year.

Powell also pointed out that the central bank has the freedom to speed up or slow down the tapering process as it sees fit. He added that markets should not expect a rate hike while the Fed is still tapering.

Tapering does depend on substantial further progress made by the U.S. economy. And if the economy continues to advance in line with expectations, the Fed could move ahead with tapering at the next meeting.

“For me, it wouldn’t take a knockout [August] employment report. It would take a reasonably good employment report for me to feel like that test is met,” Powell said. “I would say that in my own thinking, the test is all but met. I don’t personally need to see a very strong employment report. Again it’s not to be confused with the test for [rate] liftoff, which is so much higher.”

The Fed Chair was also asked about China’s Evergrande debt issue, which sparked a rout in the markets earlier this week.

“The Evergrande situation seems very particular to China, which has very high debt for an emerging economy,” Powell told reporters. “Corporate defaults in the U.S. are very low right now … You would worry that it would affect global financial conditions through confidence channels.”

When asked about the stock-trading policies for Fed officials, Powell replied that they are “not adequate” and the Fed “could do better.”

Powell noted that it is reasonable for Fed officials not to own the same assets as Fed buys. “We are going to be looking at all those things,” he said.

On the debt ceiling issue, Powell also urged Congress to raise the debt limit in a timely fashion. “It is critically important. Failure to do that is something that could result in severe damage to the economy and financial markets.”

He added that no one should assume Fed can protect the economy if the debt ceiling is not raised.

In response to Powell’s comments, gold saw some losses as markets interpreted Powell’s comments as upbeat when it came to the U.S. economy. At the time of writing, December Comex gold futures were trading at $1,767.20, down 0.62% on the day.

Live 24 hours gold chart [Kitco Inc.]

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China asks local governments to prep for Evergrande downfall: Report – CNBC Television

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