Tech
Coalition eyes 100-day target for new vaccines against disease epidemics – TheChronicleHerald.ca
By Kate Kelland
LONDON (Reuters) – An international coalition set up to prepare for future infectious disease threats set out what it called its “moonshot” plan on Wednesday to ensure new vaccines against emerging disease epidemics are developed within 100 days.
Launching a $3.5 billion five-year strategy to tackle future pandemic risks, the Coalition for Epidemic Preparedness Innovations (CEPI) said more needs to be done urgently to mitigate the threat posed by new COVID-19 variants, and to prepare for new infectious diseases.
Compressing vaccine development timelines to 100 days would make them around a third as long as it took the world to develop the first COVID-19 vaccines, CEPI said in a statement.
It called on governments, global health organisations and other partners to back what it said was a “critical investment in global health security” and to take advantage of “the revolution in vaccinology that has been catalysed by COVID-19”.
“We now have the tools to dramatically reduce or eliminate the risk of future epidemics and pandemics,” CEPI’s chief executive Richard Hatchett said. “We must invest now in the vaccines and biologic countermeasures that we need, while linking these investments with commitments to equitable access.”
CEPI, which was created in 2017 with initial donor funding from Germany, Japan and Norway and from the Bill & Melinda Gates Foundation and the Wellcome Trust global health charity, has played a key role in funding early development of a range of candidate vaccines against COVID-19.
Its plan for 2022-2026 is now focused on honing and adjusting vaccines for use against the SARS-CoV-2 and other coronaviruses, as well as preparing for as yet unknown emerging disease threats.
To be able to squeeze vaccine development timelines down to 100 days, CEPI said, researchers and drug developers would need to exploit the capabilities of so-called rapid response platform technologies, such as the mRNA approach used in COVID-19 shots developed by Pfizer-BioNtech and Moderna for example.
It would also involve working with global drugs regulators to streamline the requirements needed for vaccines to be approved, and linking-up manufacturing facilities to enable rapid production of pandemic vaccines, CEPI said.
(Editing by Angus MacSwan)
Tech
Downhill Bikes of Sea Otter – Part 2
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@juanhall: I gotta say, this was the most interesting bike in this post….love that Intense is experimenting with gearboxes…I can see it have a huge effect on DH bikes….thank god there’s still people pushing things. Now, they need to make an Enduro bike with the Pinion MGU!
Tech
Important updates regarding the Bob-Birnie Arena
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The City of Pointe-Claire would like to inform you that the Bob-Birnie arena will be closed for its annual maintenance as of Monday, April 29. The Annex rink will reopen to the public on Monday, May 13, and the arena’s Main rink will be accessible as of Monday, June 3.
Public skating will resume on May 13, and the summer public activities programming will begin on June 3 when both rinks have reopened to the public.
In addition to the annual maintenance of the facility, two renovation projects are also scheduled to start at the same time:
Installation of new sound systems
The City will be replacing its current sound systems in both the Main rink and Annex rink, to offer arena visitors a better overall experience, whether watching from the stands or participating in on-ice activities. This project is expected to be conducted throughout the month of May.
Renovation of locker rooms in the Main Rink
The City will also be renovating the five locker rooms located in the Main rink, to bring up to date the amenities currently available to participants. These renovations are expected to begin in early May and will be completed by mid-August.
For all information about the Bob-Birnie arena, visit the arena’s page on our website.
Tech
Surprise Apple Event Hints at First New iPads in Years – CNET
We haven’t seen a new iPad in years, but Apple seems likely to change that in just a few weeks. All signs point to the release of new iPad models in the first week of May.
This morning, I received an email invite for a virtual Apple event, scheduled for May 7 at 7 a.m. PT (10 a.m. ET). The invite, which says “Let Loose,” shows a drawing of a hand holding an Apple Pencil. Considering the iPad is the only device that uses the Pencil — that doesn’t leave much to the imagination.
Apple’s been expected to release new OLED-screened iPad Pros with newly designed Pencils and Magic Keyboard cases. New iPad Airs are also expected, including a larger-screened 12.9-inch model. Apple’s iPad Air lineup tends to be slightly redesigned versions of previous-model iPad Pros, so just look to the M2 iPad Pro lineup for a sense of what the next Airs could be. These would be the first new iPads since the iPad Pro M2 model arrived in late 2022.
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