NEW YORK —
Health officials in several countries are investigating mysterious cases of severe liver disease in children, and they think it may be related to a kind of virus usually associated with colds.
The U.K. has been investigating at least 74 cases in which children came down with hepatitis, or liver inflammation, the World Health Organization said Friday. Three similar cases in Spain and a few in Ireland are being investigated, the WHO said.
Meanwhile, U.S. health officials say they are looking into nine similar cases. All were in Alabama, but officials say they are looking to see if there are more elsewhere.
“Given the increase in cases reported over the past one month and enhanced case search activities, more cases are likely to be reported in the coming days,” WHO officials said in a statement.
The U.S. children ranged in age from 1 to 6 years old, and two required liver transplants. The European cases are in a similar age range, though some have been older, WHO officials said.
The WHO first became aware of the unusual illnesses early this month, when they learned of 10 children in Scotland with liver problems. One got sick in January and the nine others in March. All became severely ill and were diagnosed with hepatitis after being taken to the hospital.
The liver processes nutrients, filters the blood and fights infections. The infections caused symptoms like jaundice, diarrhea and abdominal pain. Hepatitis can be life-threatening if left untreated.
Since then, British health officials have identified at least 64 more cases. None died, but six needed liver transplants, the WHO said Friday.
Laboratory testing has ruled out the hepatitis type A, B, C and E viruses that usually cause such illnesses. Officials say they are not aware of international travel or other factors that might have put the kids at risk.
But they noted there’s been a recent surge in the spread of adenoviruses.
There are dozens of adenoviruses, many of them associated with cold-like symptoms, fever, sore throat and pink eye. But some versions can trigger other problems, including inflammation in the stomach and intestines.
Adenoviruses previously have been linked to hepatitis in children, but mostly in kids with weakened immune systems.
Some of the European children tested positive for adenovirus, and some tested positive for COVID-19. But more lab work is needed to explore any potential associations with specific viruses, the WHO said.
Alabama health officials say they have been looking into an increase in hepatitis in children since November. In each case, the child tested positive for adenovirus. Officials are exploring a link to one particular version — adenovirus 41 — that’s normally associated with gut inflammation.
None of the Alabama cases had any underlying health conditions that would seem to put them at risk for liver illness, health officials said.
“At this time adenovirus may be the cause for these, but investigators are still learning more — including ruling out the more common causes of hepatitis,” the CDC said in a statement.
Monkeypox: Cases found and suspected in Portugal, Spain – CTV News
Portuguese authorities said on Wednesday they had identified five cases of rare monkeypox infection and Spain’s health services are testing eight potential cases after Britain put Europe on alert for the virus.
The five Portuguese patients, out of 20 suspected cases, are all stable. They are all men and they all live in the region of Lisbon and the Tagus Valley, the Portuguese health authorities said.
European Health authorities are monitoring any outbreak of the disease since Britain has reported its first case of monkeypox on May 7 and found six more in the country since then.
None of the eight suspected cases in Spain has been confirmed yet, the Spanish Health Ministry said in a statement on Wednesday.
Monkeypox is a rare viral infection similar to human smallpox, though milder, first recorded in the Democratic Republic of Congo in the 1970s. The number of cases in West Africa has increased in the last decade.
Symptoms include fever, headaches and skin rashes starting on the face and spreading to the rest of the body.
It is not particularly infectious between people, Spanish health authorities said, and most people infected recover within a few weeks, though severe cases have been reported.
Four of the cases detected in Britain self-identified as gay, bi-sexual or other men who have sex with men, the U.K. Health Security Agency said, adding evidence suggested there may be a transmission in the community.
The agency in Britain urged men who are gay and bisexual to be aware of any unusual rashes or lesions and to contact a sexual health service without delay.
The Spanish Health Ministry and Portugal’s DGS health authority Spanish did not release any information on the sexual orientation of the monkeypox patients or suspected patients.
The two countries sent out alerts to health professionals in order to identify more possible cases.
(Reporting by Patricia Rua in Lisbon and Christina Thykjaer in Madrid; Editing by Inti Landauro and Alison Williams)
Long Covid Patients' Symptoms Helped After Vaccination in Study – BNN
(Bloomberg) — Fewer Covid-19 patients reported lingering symptoms from the infection after getting vaccinated, according to a study that suggests the shots could help alleviate the burden of long Covid.
A first vaccine dose after infection with the virus was associated with a 13% decline in the odds of having long Covid and a second shot with a 9% drop in the study published Thursday in the BMJ. Over the course of seven months in 2021, researchers regularly visited the households of more than 28,000 people to ask whether they were experiencing symptoms long after infection.
The findings, together with evidence that long Covid is reduced in those infected after vaccination, suggest that jabs may help decrease the prevalence of persisting symptoms.
“The large scale of this study means that we can be fairly confident about what has been observed, but it does not mean we can be sure what it means,” said Peter English, a former chair of the BMA Public Health Medicine Committee.
“The most obvious — and perhaps the most likely inference — is that vaccination does prevent at least some cases of long Covid, and may reduce the severity of symptoms,” he said in emailed comments. But “we cannot yet say this with any confidence.” English wasn’t involved in the research.
An estimated 1.8 million people in the UK had reported experiencing long Covid as of April 2022, with two in three people saying the symptoms had affected their day-to-day activities, according to the latest Office for National Statistics data.
The scientists who ran the study called for more research to “understand the biological mechanisms underpinning any improvements in symptoms after vaccination, which may contribute to the development of therapeutics for long Covid.”
©2022 Bloomberg L.P.
Europe, US on alert after new monkeypox cases emerge – Al Jazeera English
US, Spain and Portugal announce cases of rare viral infection, two weeks after UK identified its first case.
Health authorities are on alert for the spread of monkeypox, a rare viral disease first reported in the Democratic Republic of Congo in the 1970s, after new cases emerged in Europe, and the United States confirmed its first infection.
Portugal said on Wednesday it had identified five cases of monkeypox, Spain said it was testing 23 potential cases, and the US state of Massachusetts announced it had found a case in a man who recently travelled to Canada.
The United Kingdom was the first to confirm a case of monkeypox earlier this month. It has now detected seven cases and is working with the World Health Organization (WHO) to investigate the virus’s spread after being unable to make a link between the initial case, in a man who had travelled from Nigeria, and the more recent ones.
Health authorities suspect some of the infections may have occurred through sexual contact – in this instance among gay or bisexual men – with four of the UK cases identified among people who visited sexual health clinics after developing the rash associated with monkeypox.
“No source of infection has yet been confirmed for either the family or GBMSM clusters,” the WHO said in a statement in Wednesday. “Based on currently available information, infection seems to have been locally acquired in the United Kingdom. The extent of local transmission is unclear at this stage and there is the possibility of identification of further cases.”
Monkeypox, which is similar to human smallpox, typically begins with a flu-like illness and swelling of the lymph nodes, followed by a rash on the face and body. Most people recover from the illness, which is endemic in parts of central and western Africa and usually the result of close contact with infected animals, within a few weeks, but it can be fatal.
The five Portuguese patients, out of 20 suspected cases, are all in a stable condition, according to the country’s health authorities. They are all men who live in the region of Lisbon and the Tagus Valley, they added.
Health authorities in Madrid said the cases discovered in Spain appeared to be linked to sexual contact.
“In general, its transmission is via respiratory drops but the characteristics of the 23 suspected infections point to it being passed on through bodily fluids during sex relations,” they said in a statement, without giving further details.
“All of them are young adult males and most of them are men who have sexual relations with other men, but not all of them,” Elena Andradas, head of public health in the Madrid region, told Cadena Ser radio.
US health officials said the Massachusetts man who developed monkeypox went to Canada to see friends at the end of April and returned home in early May. He is currently being treated in hospital.
Jennifer McQuiston from the US Centers for Disease Control and Prevention (CDC) said while it was the only case the CDC was aware of, “I do think we are preparing for the possibility of more cases”.
The agency is in contact with its counterparts in the UK and Canada as part of the investigation, but McQuiston said no link had been established so far.
There are two types of monkeypox virus: the West African clade and Congo Basin (Central African) clade. The case-fatality ratio for the West African clade has been documented to be about 1 percent, and up to 10 percent for patients with the Congo Basin clade.
The WHO said that while smallpox vaccination has been effective against monkeypox, the end of mass vaccination programmes for smallpox meant people under the age of 40 or 50 no longer had that protection.
The UK has previously reported cases of monkeypox – all linked to travel to Nigeria – as has the US. An outbreak there in 2003 was traced to pet prairie dogs that had been housed with small animals imported from Ghana that were found to have the virus.
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