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Polio: More virus found as London kids offered shots – CTV News

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LONDON –

Children ages 1-9 in London were made eligible for booster doses of a polio vaccine Wednesday after British health authorities reported finding evidence the virus has spread in multiple areas of the city but found no cases of the paralytic disease in people.

Britain’s Health Security Agency said it detected viruses derived from the oral polio vaccine in the sewage water of eight London boroughs. The agency’s analysis of the virus samples suggested “transmission has gone beyond a close network of a few individuals.”

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The agency said it had not located anyone infected with the virus and that the risk to the wider population was low. The decision to offer young children boosters was a precaution, it said.

“This will ensure a high level of protection from paralysis and help reduce further spread,” the agency said.

The agency said it is also expanding surveillance of sewage water to at least another 25 sites in London and nationally.

Most people across Britain are vaccinated against polio in childhood. According to the World Health Organization, only one in 200 polio infections leads to paralysis; most people don’t show any symptoms.

The Health Security Agency said it was working closely with health authorities at the WHO and in the United States and Israel to investigate any links to polio viruses detected in those two countries.

Kathleen O’Reilly, a polio expert at the London School of Hygiene and Tropical Medicine, said the polio virus circulating in London was “genetically related” to recent cases identified in the U.S. and Israel.

“Further investigation is needed to fully understand how they are connected, but it does illustrate that this virus has the potential to cause disease,” O’Reilly said in a statement.

Polio is a disease often spread in water that mostly affects children under 5. It has mostly been wiped out from developed countries, but outbreaks remain in Pakistan, Afghanistan and parts of Africa.

Initial symptoms include fever, fatigue, headache, vomiting, and muscle stiffness. Among people paralyzed by the disease, death can occur in up to 10% of cases when their breathing muscles become paralyzed.

In rare cases, the live virus contained in the oral polio vaccine used in the global effort to eradicate the disease can mutate into new forms potent enough to trigger new outbreaks. The vaccination booster effort in London will use injected polio vaccines that do not carry that risk.

Experts called the finding of polio spread in London “concerning” and said the virus posed a significant risk to anyone not vaccinated.

“If (polio) continues to spread, it will result in cases of paralysis,” said Nicholas Grassly, a professor of vaccine epidemiology at Imperial College London. “It is therefore of paramount importance that children are up to date with their polio vaccines.”

Grassly said the injectable polio vaccine was less effective against stopping virus transmission than the oral vaccine and that it was possible it might be necessary to reintroduce the oral vaccine to eliminate the virus.

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RCMP warn about benzodiazepine-laced fentanyl tied to overdose in Alberta – Edmonton Journal

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Grande Prairie RCMP issued a warning Friday after it was revealed fentanyl linked to a deadly overdose was mixed with a chemical that doesn’t respond to naloxone treatment.

The drugs were initially seized on Feb. 28 after a fatal overdose, and this week, Health Canada reported back to Mounties that the fentanyl had been mixed with Bromazolam, which is a benzodiazepine.

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Mounties say this is the first recorded instance of Bromazolam in Alberta. The drug has previously been linked to nine fatal overdoses in New Brunswick in 2022.

The pills seized in Alberta were oval-shaped and stamped with “20” and “SS,” though Mounties say it can come in other forms.

Naloxone treatment, given in many cases of opioid toxicity, is not effective in reversing the effects of Bromazalam, Mounties said, and therefore, any fentanyl mixed with the benzodiazepine “would see a reduced effectiveness of naloxone, requiring the use of additional doses and may still result in a fatality.”

Photo of benzodiazepine-laced fentanyl seized earlier this year by Grande Prairie RCMP after a fatal overdose. edm

From January to November of last year, there were 1,706 opioid-related deaths in Alberta, and 57 linked to benzodiazepine, up from 1,375 and 43, respectively, in 2022.

Mounties say officers responded to about 1,100 opioid-related calls for service, last year with a third of those proving fatal. RCMP officers also used naloxone 67 times while in the field, a jump of nearly a third over the previous year.

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CFIA continues surveillance for HPAI in cattle, while sticking with original name for disease – RealAgriculture

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The Canada Food Inspection Agency will continue to refer to highly pathogenic avian influenza in cattle as HPAI in cattle, and not refer to it as bovine influenza A virus (BIAV), as suggested by the American Association of Bovine Practitioners earlier this month.

Dr. Martin Appelt, senior director for the Canadian Food Inspection Agency, in the interview below, says at this time Canada will stick with “HPAI in cattle” when referencing the disease that’s been confirmed in dairy cattle in multiple states in the U.S.

The CFIA’s naming policy is consistent with the agency’s U.S. counterparts’, as the U.S. Animal and Plant Health Inspection Service has also said it will continue referring to it as HPAI or H5N1.

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Appelt explains how the CFIA is learning from the U.S. experience to-date, and how it is working with veterinarians across Canada to stay vigilant for signs of the disease in dairy and beef cattle.

As of April 19, there has not been a confirmed case of HPAI in cattle in Canada. Appelt says it’s too soon to say if an eventual positive case will significantly restrict animal movement, as is the case with positive poultry cases.

This is a major concern for the cattle industry, as beef cattle especially move north and south across the U.S. border by the thousands. Appelt says that CFIA will address an infection in each species differently in conjunction with how the disease is spread and the threat to neighbouring farms or livestock.

Currently, provincial dairy organizations have advised producers to postpone any non-essential tours of dairy barns, as a precaution, in addition to other biosecurity measures to reduce the risk of cattle contracting HPAI.

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Toronto reports 2 more measles cases. Use our tool to check the spread in Canada – Toronto Star

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Canada has seen a concerning rise in measles cases in the first months of 2024.

By the third week of March, the country had already recorded more than three times the number of cases as all of last year. Canada had just 12 cases of measles in 2023, up from three in 2022.

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