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Russia COVID-19 vaccine may start Phase III trial in mid-Augus

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A Russian institute developing one of the country’s potential coronavirus vaccines hopes to start its final stage testing in a small section of the general public in mid-August, the RIA news agency cited the institute’s director as saying on Monday.

Globally, of 19 experimental COVID-19 vaccines in human trials, only two are in final Phase III trials – one by China’s Sinopharm and another by AstraZeneca and the University of Oxford. China’s Sinovac Biotech is set to become the third later this month.

Early results from the first small-scale human trial of the vaccine developed by the Gamaleya Institute in Moscow has shown it to be safe for use, according to a separate RIA report on Sunday.

“Around 14-15 August, I hope, the small amount of vaccine that we should be able to produce will enter public circulation,” Alexander Ginsburg, the institute’s director, was quoted as saying.

This will be equivalent to a Phase III trial, since people getting the vaccine will remain under supervision, RIA reported, citing Ginsburg.

Phase I and Phase II trials typically test the safety of a drug before it enters Phase III trials that test its efficacy on a bigger group of volunteers.

Human trials of the Gamaleya Institute’s vaccine began on June 18, with nine volunteers receiving one dose, and another nine testing the prospective booster dose.

The group did not experience any significant side effects and is due to be released from hospital on Wednesday, RIA reported on Sunday, citing a director at the Sechenov University in Moscow where the trial took place.

“Data currently available… shows the volunteers to have developed an immune response to the coronavirus vaccine,” the defense ministry, involved in the trials, was cited by RIA as saying on Monday. Another 20 volunteers were administered the vaccine at a military hospital on June 23.

Source: The Jakarta Post

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Four new COVID-19 cases in Waterloo Region on Wednesday – KitchenerToday.com

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Region of Waterloo Public Health reported four new cases of the coronavirus on Wednesday morning.

Two are due to community transmission, while the other pair are tied to travel.

So far this week, there have been 12 new cases, and a total of 1,410 since March.

The number of active cases increased by three to 25, with two of those cases currently receiving treatment in hospital.

One more case has also been resolved, improving that total to 1,263.

A total of 119 local deaths have been linked to the virus, but there have been no additional deaths reported since July 17.

Meantime, an outbreak remains active at A.R. Goudie long-term care – a resident tested positive, but no more residents or staff have since it was first declared on August 3.

Here’s the provincial COVID-19 breakdown for Wednesday:

  • 40,289 total cases (95 new)
  • 49 people are being treated in hospital
  • 36,590 resolved cases
  • 2,787 deaths (one new)

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Cape Breton's Route 19 brewery closed indefinitely after customer failed to self-isolate – Global News

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A brewery in Inverness, N.S., says it’s closing until further notice after a customer visited the restaurant on Sunday while failing to self-isolate after travelling to the province.

The Nova Scotia government still requires anyone travelling from outside of the four Atlantic provinces to self-isolate for 14 days upon arrival as a precautionary measure against the spread of the novel coronavirus.

Read more:
Nova Scotia reports no new coronavirus cases on Tuesday

Stefan Gagliardi, chief beer officer at the Route 19 Brewing Tap and Grill, told Global News on Wednesday that the brewery will remain closed as a precautionary measure.

“We found out (someone failed to self-isolate) through one of our employees who overheard a conversation elsewhere later on Sunday, and they brought it up to us,” he said over the phone.

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RCMP investigated and confirmed to Global News that they have charged a 38-year-old woman from British Columbia under the province’s Health Protection Act, which carries a $1,000 fine.






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Nova Scotians who work away from home frustrated, confused by self-isolation rules


Nova Scotians who work away from home frustrated, confused by self-isolation rules

Gagliardi said that the Nova Scotia Health Authority has told staff and visitors to Route 19 on Sunday to monitor for symptoms and to go to the 811 website for further direction if symptoms develop.

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The brewery was told it didn’t need to close as it was not a confirmed case of coronavirus, but it still left workers feeling uncertain.

It doesn’t feel good. It’s not a good feeling because our staff didn’t feel safe,” he said.

“As a business and, you know, our staff together, we decided we weren’t willing to take that risk.”

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The facility was thoroughly sanitized on Monday morning but the restaurant will remain closed until further notice.

READ MORE: Coronavirus took their lives. Here’s how their families will remember them

The closure will affect about 30 people including, kitchen and cleaning crews, bartenders, waiters and waitresses, Gagliardi said.

He says that people should follow the health recommendations set out by the province.

“It just affects us in a way that feels a little bit unfair because everybody is trying to do their best,” he said.

© 2020 Global News, a division of Corus Entertainment Inc.

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85 additional cases of COVID-19 in Alberta Tuesday, over half of them recorded in the Edmonton zone – Global News

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Alberta Health officials released the latest numbers of COVID-19 in the province Tuesday, where 85 additional cases and three new deaths were recorded.

Two men in their 70s in the Calgary zone, as well as one woman in her 80s in the North zone, died from COVID-19, although none were in continuing care centres. A total of 216 Albertans have now died due to the novel coronavirus.

The majority of new cases were in the Edmonton zone on Tuesday, with 49 new positives recorded. That number accounts for 57 per cent of Tuesday’s new cases. Edmonton zone also saw 36 new recoveries Tuesday, leaving the total active case numbers in that zone at 401.






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In the rest of the province, new cases of COVID-19 on Tuesday were much lower: Calgary zone saw nine new cases compared to an additional 50 recoveries. Central zone saw four new cases compared to 60 new recoveries, South zone recorded nine new cases versus 13 recoveries, and North zone had 12 new cases and six new recoveries. There were also two new cases and one new recovery in unknown zones.

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Net active cases in the province are down and now sit at 1,004, that’s 86 less than the day before.

Read more:
No new COVID-19 cases identified at Good Samaritan Southgate since Aug. 2

At Edmonton’s Good Samaritan care centre outbreak, another death was also recorded. Twenty-eight people at the centre have now passed away from COVID-19, although the centre typically announces its deaths ahead of them being officially announced by the province.

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The centre has not recorded any new cases of COVID-19 since Aug. 2, according to officials there.

© 2020 Global News, a division of Corus Entertainment Inc.

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