Ontario reported 1,508 new cases of COVID-19 on Wednesday, a rise from 1,074 cases confirmed the day before.
Another 14 people have died as a result of COVID-19 in Ontario, bringing the provincial death toll to 7,187.
It is the 11th day in a row that the province has reported more than 1,000 new cases, and the highest daily case count since March 8, when 1,631 cases were confirmed.
Health Minister Christine Elliott said there were 542 new infections in Toronto, 253 in Peel Region and 107 in York Region.
The latest update came as the province marked once year since the Ford government first announced a state of emergency in an effort to control the virus. A second state of emergency was declared on Jan. 12 of this year.
While the province has ramped up its vaccine rollout, the Science Table COVID-19 Advisory for Ontario says the province is now in the third wave of the pandemic.
According to recent data, variants of concern now account for almost half of current cases and continue to trend upwards while the spread of earlier variants dip.
However, despite the stats, the province’s Chief Medical Officer of Health, Dr. David Williams, said that it was still “to be determined” if the third wave had begun.
Meanwhile, an additional four cases of variants of concern were reported since the previous daily update on Tuesday, bringing the provincial total up to 1,215. A majority of the cases (1,134) are of the variant first detected in the United Kingdom.
The province tested 49,128 people for the virus on Wednesday and administered another 58,202 doses of a COVID-19 vaccine. So far, 1,301,334 doses have been administered overall.
Another 1,488 people have recovered from the virus, but 741 remain hospitalized and 300 of those patients are in intensive care.
Sanofi-GSK report positive interim results for their COVID-19 shot
An experimental COVID-19 vaccine developed by Sanofi and GlaxoSmithKline showed a robust immune response in early-stage clinical trial results, enabling them to move to a late-stage study, the French drugmaker said on Monday.
Sanofi and Britain’s GSK said a global Phase III trial would start in the coming weeks and involve more than 35,000 adults, with the hope of seeing the vaccine approved by the fourth quarter after having initially targeted the first half of this year before a setback.
Sanofi and GSK last December were forced to restart their trial when the vaccine showed a low immune response in older adults as a result of a weak antigen formulation.
Sanofi and GSK shares were little changed in early trading.
“The Phase II interim results showed 95% to 100% seroconversion following a second injection in all age groups and across all doses, with acceptable tolerability and no safety concerns,” Sanofi said.
Seroconversion refers to the vaccine’s ability to prompt the body to produce antibodies against the coronavirus, as measured by blood readings. Later mass trials will be based on real infections.
“Interestingly, we also observed that our vaccine generated a higher antibody response in those with previous COVID-19 infection, we are analysing this further as it may suggest our vaccine could serve as a potential booster, regardless of what vaccine someone may have received (beforehand),” Su-Peing Ng, Sanofi’s global head of medical for vaccines, told reporters.
Ng said the vaccine had not been tested against so-called variants in the Phase II trial but that the Phase III study would be assessing it against various strains including a virus lineage known as B.1.351 first detected in South Africa.
But Sanofi, Ng said, has conducted parallel studies evaluating its vaccines against variants, with results expected to be published soon.
GSK and Sanofi’s vaccine candidate uses the same technology as one of Sanofi’s seasonal influenza vaccines. It will be coupled with an adjuvant, a substance that acts as a booster to the shot, made by GSK.
‘QUITE A POTENTIAL’
Some 162.75 million people have been reported to be infected by the coronavirus in more than 210 countries and territories since the first cases were identified in China in December 2019, while economies have taken a hit and restrictions have turned daily life upside down.
The United States and Europe have embarked on mass vaccinations programmes in the past months, raising hopes of a gradual reopening, although the virus is still in circulation in many regions, with variants causing concern.
Last month, the European Union executive’s President Ursula von der Leyen said protein-based COVID-19 vaccines such as the one developed by Sanofi and GSK offered “quite a potential”, a positive signal as the bloc develops its purchasing strategy for the next two years.
Sanofi’s shot, however, even if approved, will come long after ones from Pfizer/BioNTech and Moderna, which have produced efficacy results of more than 90%.
So far, Sanofi has purchasing agreements with the United States, the EU, Britain and Canada, as well as with the World Health Organization-backed COVAX facility.
The company has pledged to help other drugmakers this year, striking “fill and finish” deals for vaccines made by Pfizer/BioNTech, Moderna and Johnson & Johnson.
In addition to its vaccine project in collaboration with GSK, Sanofi is working on a mRNA candidate with U.S. company Translate Bio for which it has started clinical trials.
(Reporting by Matthias Blamont; editing by Louise Heavens and Jason Neely)
Worldwide coronavirus cases cross 161.42 million, death toll at 3,488,751
More than 161.42 million people have been reported to be infected by the novel coronavirus globally and 3,488,751 have died, according to a Reuters tally.
Infections have been reported in more than 210 countries and territories since the first cases were identified in China in December 2019.
Interactive graphic tracking global spread of coronavirus: open https://tmsnrt.rs/2FThSv7 in an external browser.
Eikon users can click for a case tracker.
The following table lists the top 50 countries by the number of reported cases. A complete list is available with the above links.
COUNTRIES AND TOTAL DEATHS CONFIRMED DEATHS PER
TERRITORIES CASES 10,000
United States 584,768 32,926,288 17.9
India 262,317 24,046,809 1.94
Brazil 430,417 15,433,989 20.55
France 107,423 5,848,154 16.04
Turkey 44,301 5,095,390 5.38
Russia 254,590 4,922,901 17.62
United Kingdom 127,668 4,446,824 19.21
Italy 123,927 4,146,722 20.51
Spain 79,339 3,604,799 16.95
Germany 85,903 3,579,871 10.36
Argentina 69,254 3,242,103 15.56
Colombia 79,760 3,067,879 16.06
Poland 71,311 2,849,014 18.78
Iran 76,433 2,732,152 9.34
Mexico 219,901 2,375,115 17.43
Ukraine 47,620 2,143,448 10.67
Peru 65,316 1,873,316 20.02
Indonesia 47,823 1,734,285 1.79
Czech Republic 29,857 1,651,178 28.09
South Africa 55,012 1,605,252 9.52
Netherlands 17,423 1,589,282 10.11
Canada 24,825 1,312,408 6.7
Chile 27,520 1,266,601 14.69
Iraq 15,910 1,134,859 4.14
Philippines 18,958 1,131,467 1.78
Romania 29,413 1,070,605 15.11
Sweden 14,275 1,037,126 14.03
Belgium 24,645 1,026,473 21.56
Pakistan 19,384 873,220 0.91
Portugal 16,999 841,379 16.53
Israel 6,379 839,076 7.18
Hungary 29,041 796,390 29.71
Bangladesh 12,102 779,535 0.75
Jordan 9,203 722,754 9.24
Serbia 6,646 705,185 9.52
Switzerland 10,179 679,510 11.96
Japan 11,396 673,821 0.9
Austria 10,455 635,780 11.83
United Arab Emirates 1,626 543,610 1.69
Lebanon 7,569 534,968 11.05
Morocco 9,091 514,670 2.52
Malaysia 1,822 462,190 0.58
Nepal 4,669 439,658 1.66
Saudi Arabia 7,134 431,432 2.12
Bulgaria 17,194 413,320 24.48
Ecuador 19,442 405,783 11.38
Slovakia 12,168 387,162 22.34
Greece 11,322 373,881 10.55
Belarus 2,681 373,351 2.83
Panama 6,288 369,455 15.05
Source: Reuters tally based on statements from health ministries and government officials
Generated at 10:00 GMT.
(Editing by David Clarke)
Canada plots course to fully vaccinated return to gatherings in fall
Canada on Friday said there would be a gradual return to a world with indoor sports and family gatherings as more people get vaccinated, but it did not go as far as the United States in telling people they could eventually ditch their masks.
Canada has administered one dose of a COVID-19 vaccine to just over half its adult population, and the country may be over the worst of its current third wave of infections, Chief Public Health Officer Theresa Tam said.
On Thursday, the U.S. Centers for Disease Control and Prevention (CDC) advised that fully vaccinated people do not need to wear masks outdoors and can avoid wearing them indoors in most places, guidance the agency said will allow life to begin to return to normal.
On Friday, Canada‘s public health agency offered guidelines to the 10 provinces, which are responsible for public health restrictions.
The agency says once 75% of Canadians have had a single dose and 20% are fully vaccinated, some restrictions can be relaxed to allow small, outdoor gatherings with family and friends, camping, and picnics.
Once 75% of those eligible are fully vaccinated in the fall, indoor sports and family gatherings can be allowed again.
“I think masks might be the last layer of that multi-layer protection that we’ll advise people to remove,” Tam told reporters, noting that in Canada colder temperatures meant people would start spending more time indoors in the fall.
“We are taking a bit of a different approach to the United States,” she added. While in most of Canada masks are not required outdoors, they are mandatory indoors.
Less than 4% of Canada‘s adult population has been fully vaccinated compared to more than 36% of Americans.
Prime Minister Justin Trudeau, who has promised that everyone who wants to can be fully vaccinated by September, this week spoke of a “one-dose summer” and a “two-dose fall” without explaining what that might look like.
(Reporting by Steve Scherer and David Ljunggren; Editing by Hugh Lawson)
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