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Researchers investigate potential links between sleep disturbances and stroke

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The dynamics between stroke and sleep – measured in both quantity and quality -; are complex. Research has broadly shown that either sleep deprivation or sleeping for longer than 9 hours a day can increase the risk of having a stroke. Having a stroke can also cause changes in sleeping patterns.

Given the massive impact of stroke on global public health, better understanding its connections with sleep disturbances couldn’t be more important.

Now, a new study led by a uOttawa Faculty of Medicine research team, investigates the prevalence of sleep disturbances in Canadian adults for potential associations with stroke, a leading cause of death or disability that occurs when blood supply is blocked to part of the brain or a blood vessel hemorrhages in the brain. Their findings could help inform target interventions.

Published today in the Canadian Medical Association Journal (CMAJ), here’s what the population-based study shows: Almost two-thirds of those with stroke in Canada show symptoms of disturbed sleep. And people living with the effects of stroke were up to 7 times more likely to report multiple sleep problems compared to the general population, according to the study.

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That’s significant because the current guidelines for stroke care by the Canadian Stroke Best Practices only briefly mention sleep problems in the context of post-stroke fatigue.

So what might family physicians and stroke specialists glean from this study moving forward?

Matthew Jeffers, a PhD student in the Faculty’s School of Epidemiology and Public Health who is the study’s first author, says greater awareness, guidance for treatment, and research on how to manage sleep problems in the context of stroke is needed considering that these disturbances affect the majority of those with stroke across Canada.

Our overall goal for practitioners in the primary care setting is to increase their awareness of the high number of stroke patients with sleep disturbance symptoms. Given how common this is, it may be worthwhile for physicians to consider screening for underlying sleep disorders in patients with stroke.”

Matthew Jeffers, PhD student in the Faculty’s School of Epidemiology and Public Health

One of the paper’s reviewers described it as a “well written and designed study” that “provides data on an important topic that, as the authors correctly point out, is lacking in the literature.”

To complete this study, the research team employed various statistical techniques for a cross-sectional analysis of the Canadian Community Health Survey (CCHS), a large and comprehensive national survey on people’s health status and the determinants of health.

This gave them a far better picture of how common sleep problems are in stroke across the Canadian population than previous studies, which typically have small sample sizes.

Jeffers suggests that further research will be necessary to study groups of patients in sleep labs to get a more thorough and objective understanding of the relationship between stroke and specific types of sleep disorders, such as sleep apnea and insomnia.”

Jeffers first proposed this study during a course in Epidemiological Methods & Applications taught by Dr. Yue Chen, who helped him turn it into a publication and was one of several co-authors. He received statistical analysis help from Dr. Marie-Hélène Roy-Gagnon and support from his Faculty supervisors, Dr. Dean Fergusson and Dr. Manoj Lalu.

Journal reference:

Jeffers, M. S., et al. (2023) Open Access Self-reported sleep disturbances among people who have had a stroke: a cross-sectional analysis. CMAJ. doi.org/10.1503/cmaj.221063.

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It's possible to rely on plant proteins without sacrificing training gains, new studies say – The Globe and Mail

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At the 1936 Olympics in Berlin, a scientist named Paul Schenk surveyed the eating habits of top athletes from around the world. The Canadians reported plowing through more than 800 grams of meat per day on average; the Americans were downing more than two litres of milk daily.

While there have been plenty of changes in sports nutrition since then, the belief that meat and dairy are the best fuel for building muscle persists. These days, though, a growing number of athletes are interested in reducing or eliminating their reliance on animal proteins, for environmental, ethical or health reasons. A pair of new studies bolsters the case that it’s possible to rely on plant proteins without sacrificing training gains, as long as you pick your proteins carefully.

The standard objection to plant proteins is that they don’t have the right mix of essential amino acids needed to assemble new muscle fibres. Unlike animal proteins, most plant proteins are missing or low in at least one essential amino acid.

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In particular, there’s one specific amino acid, leucine, that seems to play a special role in triggering the synthesis of new muscle. It’s particularly abundant in whey, one of the two proteins (along with casein) found in milk. That’s why whey protein is the powdered beverage of choice in gyms around the world, backed by decades of convincing research, which was often funded by the dairy industry.

But one of the reasons whey looks so good may be that we haven’t fully explored the alternatives. A 2018 study by Luc van Loon of the University of Maastricht in the Netherlands, for example, tested nine vegetable proteins including wheat, hemp, soy, brown rice, pea and corn. To their surprise, they found that corn protein contains 13.5 per cent leucine – even more than whey.

Based on that insight, van Loon decided to pit corn against milk in a direct test of muscle protein synthesis. Volunteers consumed 30 grams of one of the proteins; a series of blood tests and muscle biopsies were collected over the next five hours to determine how much of the ingested protein was being turned into new muscle fibres. The results, which appeared in the journal Amino Acids, were straightforward: Despite all the hype about whey, there was no discernible difference between them.

A second study, this one published in Medicine & Science in Sports & Exercise by a team led by Benjamin Wall of the University of Exeter in Britain, had similar findings. Instead of corn, it used a mix of 40 per cent pea, 40 per cent brown rice and 20 per cent canola proteins. Since different plants have different amino acids profiles, mixing complementary proteins has long been suggested as a way overcoming the deficiencies of any single plant protein. Sure enough, the protein blend triggered just as much new muscle synthesis as whey.

On the surface, the message from these studies is straightforward: Plant proteins are – or at least can be – as effective as even the best animal proteins for supporting muscle growth. There are a few caveats to consider, though. One is that the studies used isolated protein powders rather than whole foods. You would need nearly nine cobs of corn to get the 30 grams of protein used in van Loon’s study, compared to just three-and-a-half cups of milk.

Another is that plants are generally harder to digest, meaning that not all the amino acids will be usable. That may not be a problem for healthy young adults consuming 30 grams of protein at once, which is enough to trigger a near-maximal muscle response. But for older people, who tend to have blunted muscle-building responses to protein, or in situations where you’re getting a smaller dose of protein, the details of protein quality may become more important.

Of course, the effectiveness of plant proteins won’t be news to notable plant-based athletes such as ultrarunner Scott Jurek or basketball star Chris Paul – but it’s encouraging to see the science finally begin to catch up.

Alex Hutchinson is the author of Endure: Mind, Body, and the Curiously Elastic Limits of Human Performance. Follow him on Threads @sweat_science.

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See how chicken farmers are trying to stop the spread of bird flu – Fox 46 Charlotte

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CLOVER, S.C. (QUEEN CITY NEWS) — Poultry farmers across the Carolinas aren’t taking any chances.  Many are turning to strict protocols as another wave of bird flu continues to threaten the chicken population across the country. 

Since 2022, it is estimated more than 90 million birds have either died from the virus or were killed to prevent further spread in the U.S. 

“We try to make them the happiest as possible. We always say a happy chicken is a tasty chicken,” owner of Eden Farms Adam Shumate said. 

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With their happiness in mid, Shumate also wants to keep his chickens alive and healthy. On his farm in Clover, he has implemented protocols to minimize a potential bird flu outbreak.  

“We want to be prepared,” he said. “We feel like the things that we can do to prevent it first is the best case because we don’t want to start from scratch with a whole new flock.”  

Because bird flu is commonly spread through bird droppings, Shumate is limiting the number of people coming into contact with his flocks. He says this would minimize the chances of someone walking onto the property with bird droppings on the bottoms of their shoes. 

On top of monitoring the chickens closely, Shumate and his staff are constantly cleaning their equipment, including what they wear on their feet.   

“We have specific shoes that are just for working with the flock and for when we are taking care of them,” Shumate said. 

Other farmers, like Holly Burrell, haven’t let a visitor step foot near her hens in Gastonia for more than two years. 

No visitors or outside cars are welcomed, and her chickens are separated in what she calls “tent cities.” 

“We don’t want to do that because we want them to live their best life,” Burrell said in a 2022 interview with Queen City News. 

Recently, health officials have detected bird flu in other animals like seals, squirrels and dolphins. 

Earlier this month, bird flu was detected in one of the state’s dairy cow herds. While concerning, state health officials say the overall risk to the general public remains low. 

“I’ve not heard of any cases, zero cases of people being affected by this virus associated with food consumption, milk consumption with egg consumption… any of these products we’re getting from farm animals is not really been associated with any human risk at this point,” said Dr. Michael Martin, director of the Veterinary Division at the N.C. Department of Agriculture and Consumer Services. 

As of March 28, at least 80 birds in North Carolina were detected with the virus. Back in York County, Shumate says it all starts with the individual farms. 

“When it comes to wildlife and things that that, there is only so much that you can do is be observant,” Shumate said. “Keep a healthy flock that way they can find off the infections that may come about.” 

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CFIA Monitoring for Avian Influenza in Canadian Dairy Cattle After US Discoveries – Morning Ag Clips –

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From the field to your inbox, the Weekend Edition of the Morning Ag Clips features stories, trends, and unique perspectives from the farming community. This laid-back edition is great for anyone looking for a fun weekend read.

Morning Ag Clips. All ag. All the time.

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