Prostate cancer treatment can wait for most men, study finds – The Associated Press – en Español
Researchers have found long-term evidence that actively monitoring localized prostate cancer is a safe alternative to immediate surgery or radiation.
The results, released Saturday, are encouraging for men who want to avoid treatment-related sexual and incontinence problems, said Dr. Stacy Loeb, a prostate cancer specialist at NYU Langone Health who was not involved in the research.
The study directly compared the three approaches — surgery to remove tumors, radiation treatment and monitoring. Most prostate cancer grows slowly, so it takes many years to look at the disease’s outcomes.
“There was no difference in prostate cancer mortality at 15 years between the groups,” Loeb said. And prostate cancer survival for all three groups was high — 97% regardless of treatment approach. “That’s also very good news.”
The results were published Saturday in the New England Journal of Medicine and presented at a European Association of Urology conference in Milan, Italy. Britain’s National Institute for Health and Care Research paid for the research.
Men diagnosed with localized prostate cancer shouldn’t panic or rush treatment decisions, said lead author Dr. Freddie Hamdy of the University of Oxford. Instead, they should “consider carefully the possible benefits and harms caused by the treatment options.”
A small number of men with high-risk or more advanced disease do need urgent treatments, he added.
Researchers followed more than 1,600 U.K. men who agreed to be randomly assigned to get surgery, radiation or active monitoring. The patients’ cancer was confined to the prostate, a walnut-sized gland that’s part of the reproductive system. Men in the monitoring group had regular blood tests and some went on to have surgery or radiation.
Death from prostate cancer occurred in 3.1% of the active-monitoring group, 2.2% in the surgery group, and 2.9% in the radiation group, differences considered statistically insignificant.
At 15 years, cancer had spread in 9.4% of the active-monitoring group, 4.7% of the surgery group and 5% of the radiation group. The study was started in 1999, and experts said today’s monitoring practices are better, with MRI imaging and gene tests guiding decisions.
“We have more ways now to help catch that the disease is progressing before it spreads,” Loeb said. In the U.S., about 60% of low-risk patients choose monitoring, now called active surveillance.
Hamdy said the researchers had seen the difference in cancer spread at 10 years and expected it to make a difference in survival at 15 years, “but it did not.” He said spread alone doesn’t predict prostate cancer death.
“This is a new and interesting finding, useful for men when they make decisions about treatments,” he said.
The Associated Press Health and Science Department receives support from the Howard Hughes Medical Institute’s Science and Educational Media Group. The AP is solely responsible for all content.
Healthy Kids, Adolescents May Not Need Covid Shots, WHO Says – BNN Bloomberg
(Bloomberg) — Healthy children and adolescents may no longer need Covid shots, the World Health Organization said, updating its guidance on vaccines as the world adjusts to living permanently with the virus.
Older people and higher-risk groups — including those with underlying conditions — should get Covid boosters between six and 12 months after their last injections, the WHO said in a statement announcing a revised vaccine road map for the new stage of the pandemic.
“Countries should consider their specific context in deciding whether to continue vaccinating low-risk groups, like healthy children and adolescents, while not compromising the routine vaccines that are so crucial for the health and well-being of this age group,” said Hanna Nohynek, chair of the WHO’s Strategic Advisory Group of Experts on Immunization.
The Geneva-based organization’s latest advice comes as booster rates fall in countries from China to the US, with just 16% of Americans lining up for the latest round of shots targeting the omicron variant, Bloomberg reported earlier this month.
The dropoff won’t just have financial consequences for vaccine makers — including Pfizer Inc. and Moderna Inc. — but is also sparking concerns among public health experts who say updated vaccinations are the best way to protect against Covid.
Read more: Covid Boosters Sour for Pfizer, Moderna With Uptake Rate at 16%
Healthy children between the ages of 6 months and 17 years are a low-priority group for vaccination, the WHO said, and primary and booster doses are safe and effective for them. They have typically experienced less severe reactions to Covid than adults.
The WHO said context mattered in deciding whether to inoculate younger people given the lower burden of disease.
The organization “urges countries considering vaccination of this age group to base their decisions on contextual factors, such as the disease burden, cost effectiveness, and other health or programmatic priorities and opportunity costs,” the statement said.
–With assistance from Tanaz Meghjani.
©2023 Bloomberg L.P.
Reasons Why The Keto Diet And Crossfit Training Are Growing Trends Across Georgia
The ketogenic diet, or “keto” diet, is a high-fat, low-carb diet that has gained popularity in recent years due to its potential health benefits. The diet aims to induce a metabolic state called ketosis, where the body burns fat for fuel instead of carbohydrates. This can result in weight loss and improved blood sugar control, among other benefits.
Crossfit training is a high-intensity, functional fitness program that combines elements of weightlifting, gymnastics, and cardio. It is designed to improve overall fitness and performance in a variety of physical activities.
When coupled, the ketogenic diet and CrossFit exercise have the potential to be an effective strategy for both weight reduction and an increase in overall physical capability. The ketogenic diet supplies the body with a consistent supply of energy, which may assist in the improvement of endurance while doing Crossfit activities. Moreover, it may assist in the healing of muscles and decrease inflammation.
Nevertheless, it is essential to keep in mind that the ketogenic diet may not be appropriate for everyone, particularly those who are dealing with certain health concerns. Before beginning any new eating plan or workout routine, it is essential to discuss the changes with a qualified medical practitioner.
Those who are wanting to enhance their physical fitness and general health may find that combining Crossfit exercise with the ketogenic diet is a combination that is advantageous to their goals. You may read the reasons why the keto diet and crossfit workout are becoming more popular throughout Georgia in the following paragraph.
Improved endurance during workouts
One of the primary reasons why the ketogenic diet and Crossfit training are becoming more popular in Georgia is that they both lead to improvements in exercise endurance. The ketogenic diet encourages fat burning inside the body, which, in comparison to the breakdown of carbs for fuel, results in a more consistent and sustained supply of energy. Because of this, people are able to keep up their energy levels even throughout lengthy and strenuous CrossFit sessions, which ultimately leads to increased endurance.
Training in CrossFit, on the other hand, is intended to increase not just general physical fitness but also performance in other aspects of the body, including endurance. Workouts at CrossFit are known for their high levels of intensity, which provide a challenge to the body and force people to test the boundaries of their capabilities. As a consequence, over time, individuals see improvements in their endurance.
Since the keto diet provides the body with a consistent supply of energy that it can utilize throughout exercises and Crossfit training pushes the body to develop its endurance capacities, the combination of the two may be especially helpful in increasing endurance. Because of this, a significant number of people in Georgia are turning to this potent combination in order to boost their physical fitness and overall performance.
Increased weight loss
Both the ketogenic diet and Crossfit exercise have become more popular in Georgia for a number of reasons, one of the most important of which is weight reduction. The ketogenic diet is designed to guide individuals into a metabolic state known as ketosis, in which the body uses fat for fuel rather than carbs. This may result in considerable weight reduction, particularly when paired with regular Crossfit activities, which help burn calories and build muscle at the same time.
Georgia residents who are interested in this powerful combination can find resources and support through local gyms and fitness centers that offer Crossfit training and nutrition coaching. In addition, Georgia real estate listings often include properties with home gyms, making it easier than ever for individuals to incorporate regular workouts into their daily routines. Overall, the keto diet and Crossfit training are growing trends across Georgia due to their proven effectiveness in improving physical fitness, performance, and weight loss. With the right resources and support, anyone in Georgia can benefit from this powerful combination and achieve their health and fitness goals.
Better blood sugar control
Another reason why the keto diet and Crossfit workouts are becoming more popular throughout the state of Georgia is that they help better regulate blood sugar levels. By limiting the consumption of carbs, which are known to produce rises in blood sugar levels, the ketogenic diet is thought to be beneficial for helping to control blood sugar levels. Those who have diabetes or other diseases connected to high blood sugar may benefit from this in a particularly significant way.
Crossfit training, on the other hand, can also help improve blood sugar control by increasing insulin sensitivity and glucose uptake by the muscles. This means that the body is better able to process and utilize glucose, resulting in more stable blood sugar levels.
Overall, the combination of the keto diet and Crossfit training can be a powerful tool for better blood sugar control, leading to improved overall health and well-being. Georgia residents who are interested in this approach can find support through local gyms and fitness centers that offer Crossfit training and nutrition coaching.
Improved muscle recovery
Improved muscle recovery is another reason why the keto diet and Crossfit training are growing trends across Georgia. The keto diet provides the body with a steady source of energy, which can aid in muscle recovery after Crossfit workouts. Additionally, the diet is high in protein, which is essential for repairing and building muscle tissue.
Crossfit training itself can also help improve muscle recovery by increasing blood flow and nutrient delivery to the muscles. This can help reduce muscle soreness and improve recovery time between workouts.
The combination of the keto diet and Crossfit training can be particularly effective in improving muscle recovery, as the diet provides the necessary nutrients and energy for muscle repair and growth, while Crossfit training challenges the muscles and promotes blood flow.
Overall, the keto diet and Crossfit training are growing trends across Georgia due to their ability to improve physical fitness, performance, and muscle recovery.
Reduced inflammation is another reason why the keto diet and Crossfit training are growing trends across Georgia. Inflammation is the body’s natural response to injury or infection, but chronic inflammation can contribute to a variety of health problems.
By limiting the consumption of items that are known to cause inflammation, such as sugar and processed carbohydrates, the ketogenic diet has been shown to have anti-inflammatory effects. This may assist in reducing inflammation throughout the body, which may ultimately contribute to improvements in general health.
Crossfit training may also help decrease inflammation since it increases blood flow and nutrition supply to the muscles, both of which can assist in healing and reduce inflammation. Crossfit training is also known as functional fitness.
The combination of the keto diet and Crossfit training can be particularly effective in reducing inflammation, as the diet provides the necessary nutrients and energy for muscle repair and growth, while Crossfit training challenges the muscles and promotes blood flow.
Improved physical performance
Improved physical performance is one of the primary reasons why the keto diet and Crossfit training are growing trends across Georgia. The keto diet provides the body with a steady source of energy, which can improve physical performance during Crossfit workouts. The diet’s high-fat content can also aid in muscle recovery and reduce inflammation, leading to improved overall physical performance.
Crossfit training is designed to improve overall physical fitness and performance, including strength, endurance, and agility. The high-intensity nature of Crossfit workouts challenges the body and pushes individuals to their limits, resulting in improved physical performance over time.
The combination of the keto diet and Crossfit training can be particularly effective in improving physical performance, as the diet provides the necessary nutrients and energy for muscle repair and growth, while Crossfit training challenges the muscles and promotes overall physical fitness.
Increased energy levels
Increased energy levels are another reason why the keto diet and Crossfit training are growing trends across Georgia. The keto diet helps the body enter a state of ketosis, where it burns fat instead of carbohydrates for fuel. This leads to a more sustained and stable energy level throughout the day, reducing fatigue and increasing overall energy levels.
Moreover, improved energy levels are promoted by Crossfit exercise since it forces the body to make better use of the energy resources it already has. The high degree of intensity that characterizes Crossfit exercises may produce an endorphin surge, which not only increases energy levels but also improves mood.
Since the keto diet supplies the body with a consistent stream of energy that it may utilize throughout workouts and Crossfit exercise pushes the body to improve its general energy efficiency, the combination of the two can be especially helpful in improving levels of energy.
As a whole, the keto diet and Crossfit exercise are becoming more popular across the state of Georgia due to their capacity to raise levels of energy and enhance overall physical fitness and performance.
Improved mental clarity
Improved mental clarity is another reason why the keto diet and Crossfit training are growing trends across Georgia. The keto diet provides a steady source of energy for the brain, which can improve mental clarity and focus. This is because the brain requires a stable supply of energy to function optimally.
In addition to this, regular Crossfit workouts have been shown to boost mental acuity by increasing blood flow and nutrition supply to the brain. It has been shown that engaging in physical activity may enhance cognitive function and lower the risk of cognitive decline.
Because the keto diet supplies the necessary nutrients and energy for brain function while Crossfit training challenges the body and increases blood flow to the brain, the combination of the two can be particularly effective in improving mental clarity. This is due to the fact that the diet provides the necessary nutrients and energy for brain function.
Reduced appetite is another reason why the keto diet and Crossfit training are growing trends across Georgia. The keto diet is known to reduce appetite by increasing feelings of fullness and reducing cravings, which can lead to reduced calorie intake and weight loss. This is because the high fat content of the diet promotes satiety and reduces the need for frequent snacking.
Increasing your metabolic rate and the number of calories you burn via CrossFit may also help you feel less hungry. This indicates that those who participate in regular Crossfit exercises may see a natural reduction in their levels of hunger throughout the day.
Because the keto diet supplies the body with a consistent source of energy and Crossfit training challenges the body and speeds up the metabolic rate, the combination of the two can be particularly effective in suppressing appetite and fostering weight loss. This is due to the fact that the diet helps the body maintain a constant source of energy while also promoting weight loss.
Improved insulin sensitivity
Improved insulin sensitivity is another reason why the keto diet and Crossfit training are growing trends across Georgia. The keto diet can help improve insulin sensitivity by reducing the intake of carbohydrates, which are known to cause spikes in blood sugar and decrease insulin sensitivity over time. This means that the body is better able to respond to insulin and process glucose more efficiently.
Crossfit training can also improve insulin sensitivity by promoting muscle growth and glucose uptake by the muscles. This means that the body is better able to utilize glucose for energy, leading to improved insulin sensitivity.
The combination of the keto diet and Crossfit training can be particularly effective in improving insulin sensitivity, as the diet provides a stable source of energy for the body and reduces the intake of inflammatory foods, while Crossfit training challenges the muscles and promotes glucose uptake.
Both the ketogenic diet and Crossfit exercise are becoming more popular throughout the state of Georgia as a result of their capacity to enhance insulin sensitivity, mental clarity, physical fitness, and weight reduction while simultaneously reducing inflammation and hunger. Local gyms and fitness facilities in Georgia that also provide nutrition coaching are great places for locals to go for help.
MUHC opens Quebec’s first multidisciplinary referral centre for endometriosis
Montreal, March 28, 2023 – The McGill University Health Centre (MUHC) is proud to launch Quebec’s first multidisciplinary referral centre for multisystem endometriosis. EndoCARES, or the Endometriosis Centre for the Advancement of REsearch and Surgery, aims to provide patients suffering from pain and infertility due to endometriosis with timely access to specialized diagnostic imaging, followed by multidisciplinary care based on individual needs.
Endometriosis is an inflammatory condition where endometrial-like tissue (similar to the inner lining of the uterus) grows outside of the uterus. Affecting about 1 in 10 women of reproductive age, it commonly causes infertility and debilitating pelvic pain, often severe enough to limit a woman’ s ability to carry out normal daily activities.
“While half of women with infertility and up to 70 per cent of those with chronic pelvic pain have endometriosis, studies show an average delay of seven years from the start of symptoms to diagnosis,” explains Dr. Togas Tulandi, chief of the Department of Obstetrics and Gynecology at the MUHC. “EndoCARES aims to significantly reduce this delay by uniting a team of gynecologic surgeons specialized in minimally invasive surgery – more specifically, in the removal of endometriosis lesions – along with other specialists, such as bowel surgeons, urologists, radiologists and fertility specialists, in a single patient-centered clinic.”
EndoCARES specialists come together regularly to discuss complex surgical cases and devise the best treatment strategies to offer patients. Meanwhile, a dedicated nursing staff provides continuity of care for the patients by facilitating the coordination of care between specialists and monitoring post-operative recovery following complex surgeries.
A centre of excellence
Drs. Dong Bach Nguyen and Andrew Zakhari, co-directors of the centre, both pursued additional training at renowned endometriosis hubs in Europe after completing minimally invasive surgery fellowships in Ottawa and Toronto respectively. As a result, patients treated at EndoCARES now benefit from innovative surgeries specific to endometriosis not previously offered in Quebec. “In Europe, several countries have established centres of excellence to provide specialized care to patients affected by endometriosis. Training in these centres allowed us to bring back not only new surgical techniques, but also the foundations to build an endometriosis referral centre for women with multi-organ endometriosis in Quebec,” explains Dr. Nguyen.
“The primary objective of this centre is to provide women with severe endometriosis affecting other organs like the bladder,bowel or diaphragm, with dedicated surgical and radiological expertise,” says Dr. Zakhari. Along with Drs. Srinivasan Krishnamurthy, Fady Mansour, Jessica Papillon-Smith and Togas Tulandi, this team of surgical gynecologists is committed to improving the care of Quebec women suffering from endometriosis.
Many questions remain unanswered
“Today, we still do not understand the exact cause of endometriosis, nor do we have a cure,” explains Dr. Tulandi, who is also an associate investigator at the Child Health and Human Development Program at the Research Institute of the MUHC.
Moving forward, EndoCARES aims to enhance basic, epidemiological and clinical research in endometriosis with the establishment of a patient registry that will function as a database for future research. Additionally, the program will facilitate international networking, collaborative research and the standardization of clinical practice through the exchange of ideas and experiences.
EndoCARES’ state-of-the-art clinical care and forthcoming research are made possible in part by generous donations made to the MUHC Foundation, which has pledged to raise $700,000 in support of personnel and equipment for the EndoCARES program.
“Endometriosis is very common and yet, so many women endure years of pain before receiving a diagnosis. This is completely unacceptable. The MUHC Foundation is proud to support the EndoCARES program, because it will change women’s health care for the better and reduce the pain and uncertainty so many women endure,” says Julie Quenneville, president and CEO of the MUHC Foundation.
Someone to reach out to
It took five long years before Anisa Gjoka was referred to Dr. Andrew Zakhari and diagnosed with stage 4 endometriosis at 25 years old. “On February 8, 2021, in the middle of a pandemic, I finally had my surgery,” recounts Anisa. “After a four-hour surgery, and with only four small incisions, they were able to carefully remove the endometriosis lesions, leaving all of my organs intact!”
Today, at 28 years old, Anisa maintains a pain-free lifestyle, something that seemed unimaginable before entering under the expert care of Dr. Zakhari. “It gives me great peace of mind to know that EndoCARES exists – that there is finally someone for me to reach out to whenever I’m in need, and that the young women experiencing their first symptoms will be spared years of suffering and will be cared for by a multidisciplinary team of experts, all in one place.”
About the McGill University Health Centre
The McGill University Health Centre (MUHC) is one of the world’s foremost academic health facilities. Building on the tradition of medical leadership of its founding hospitals, the MUHC provides exceptional multidisciplinary patient-centric care in French and in English. Affiliated with the Faculty of Medicine and Health Sciences of McGill University, the MUHC continues to shape the course of adult and pediatric medicine by attracting clinical and research expertise from around the world, assessing the latest in medical technology, and training the next generation of medical professionals. In collaboration with our network partners, we are building a better future for our patients and their families; for our employees, professionals, researchers and students; for our community and above all, for life. www.muhc.ca
McGill University Health Centre
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